Two-year bronchodilator treatment in patients with mild airflow obstruction: contradictory effects on lung function and quality of life

CP van Schayck, MPMH Rutten-van Mölken… - Chest, 1992 - Elsevier
In a two-year randomized controlled study, we studied the effects of bronchodilator treatment
on the lung function and the quality of life in patients with mild airflow obstruction. The …

Independent influence of reversibility of air-flow obstruction and nonspecific hyperreactivity on the long-term course of lung function in chronic air-flow obstruction

DS Postma, K de Vries, GH Koëter… - American review of …, 1986 - atsjournals.org
We evaluated factors that might influence the course of lung function after 2 to 21 yr of follow-
up in 81 nonallergic patients with chronic air-flow obstruction (CAO) and considerable lung …

Bronchodilators in chronic air-flow limitation: effects on airway function, exercise capacity, and quality of life

GH Guyatt, M Townsend, SO Pugsley… - American Review of …, 1987 - atsjournals.org
We conducted a trial of inhaled salbutamol and orally administered theophylline in patients
whose acute response to inhaled salbutamol was less than 25% of their baseline FEV1 …

Severe chronic airflow obstruction: can corticosteroids slow down progression?

DS Postma, EJ Steenhuis… - European journal of …, 1985 - europepmc.org
A long-term (14-18 yr) prognostic study on patients with severe Chronic Airflow Obstruction
(CAO)(FEV1 less than 1000 ml) is reported. In 65 of the 79 patients under study at least 7 …

Mechanism of bronchodilator effect in chronic airflow limitation.

R Jaeschke, GH Guyatt, J Singer, J Keller… - CMAJ: Canadian …, 1991 - ncbi.nlm.nih.gov
OBJECTIVE: To examine the mechanisms through which two bronchodilators (theophylline
and salbutamol) influence dyspnea during daily activities. METHODS: Twenty-four patients …

The effect of increasing doses of β-agonists on airflow in patients with chronic airflow limitation

R Jaeschke, GH Guyatt, D Cook, J Morris, A Willan… - Respiratory …, 1993 - Elsevier
Objective: To determine the increase in FEV 1 associated with increasing doses of inhaled
terbutaline and salbutamol, the reproducibility of the increase in FEV 1, and the …

Moderately severe chronic airflow obstruction. Can corticosteroids slow down obstruction?

DS Postma, I Peters, EJ Steenhuis… - European Respiratory …, 1988 - Eur Respiratory Soc
In a former study in patients with severe chronic airflow obstruction (CAO),(forced expiratory
volume in one second (FEV1) ranging from 350-910 ml), we concluded that daily oral …

Assessment of reversibility of airway obstruction in patients with chronic obstructive airways disease.

M Nisar, M Walshaw, JE Earis, MG Pearson… - Thorax, 1990 - thorax.bmj.com
Spirometry before and after an inhaled beta agonist or a course of oral prednisolone is
widely used to detect reversible airflow limitation in patients with chronic obstructive lung …

Acute response to bronchodilator: an imperfect guide for bronchodilator therapy in chronic airflow limitation

GH Guyatt, M Townsend, S Nogradi… - Archives of Internal …, 1988 - jamanetwork.com
• We conducted a four-period cross-over randomized trial in which we found that patients
with chronic airflow limitation demonstrated symptomatic improvement with both inhaled …

[引用][C] The use of bronchodilators in stable chronic obstructive pulmonary disease

M Cazzola, D Spina, MG Matera - Pulmonary pharmacology & therapeutics, 1997 - Elsevier
The Use of Bronchodilators in Stable Chronic Obstructive Pulmonary Disease Page 1 Pulmonary
Pharmacology & Therapeutics (1997) 10, 129–144 PULMONARY PHARMACOLOGY & …