On one side, brain dysfunction is a poorly explored complication of sepsis. On the other side,
brain dysfunction may actively contribute to the pathogenesis of sepsis. The current review …

Sepsis is a major health problem all over the world. Despite its existence since the time of
Hippocrates (470 BC), sepsis is still a serious medical problem for physicians working in …

Sepsis is a systemic, deleterious inflammatory host response triggered by an infective agent
leading to severe sepsis, septic shock and multi-organ failure. The host response to infection …

Overwhelming inflammatory immune response can result in systemic inflammation and
septic shock. To prevent excessive and deleterious action of proinflammatory cytokines after …

Sepsis remains the leading cause of death in the ICU. Considering the key role of the
immune system in sepsis, immunomodulation represents an attractive target for adjunctive …

Sepsis, which is a highly heterogeneous syndrome, can result in death as a consequence of
a systemic inflammatory response syndrome. The activation and regulation of the immune …

Objectives Immunological dysregulation is now recognised as a major pathogenic event in
sepsis. Stimulation of immune response and immuno-modulation are emerging approaches …

Background: The immune system protects the host against dangerous pathogens and
toxins. The central nervous system is charged with monitoring and coordinating appropriate …

Sepsis is known since the time (470 BC) of great Greek physician, Hippocrates.
Advancement in modern medicine and establishment of separate branches of medical …

Sepsis occurs when a systemic infection induces an uncontrolled inflammatory response
that results in generalized organ dysfunction. The exacerbated peripheral inflammation can …