Sepsis is currently defined as a life-threatening organ dysfunction caused by a dysregulated
host response to infection, and it affects over 25 million people every year. Even more …

Objective: Summarize the current knowledge on the role of the hypothalamic pituitary axis in
the development of sepsis. Design: Review article. Method: We systematically searched for …

The systemic inflammatory response syndrome (SIRS) and sepsis are accompanied by a
complex, unbalanced and often fatal activation of the immune and inflammatory systems …

Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
responses to infection (Third International Consensus definition for Sepsis and septic …

The inflammatory response is modulated through interactions among the nervous,
endocrine, and immune systems. Intercommunication between immune cells and the …

Sepsis with subsequent multiple organ dysfunction is a pronounced systemic inflammatory
response to concealed or known infection and is a leading cause of death in intensive care …

Sepsis is a systemic inflammatory response induced by an infection, leading to organ
dysfunction and mortality. Historically, sepsis-induced organ dysfunction and lethality were …

Immunomodulation has long been an adjunct approach in treating critically ill patients with
sepsis, acute respiratory distress syndrome (ARDS), and acute pancreatitis (AP) …

It has recently been appreciated that patients with severe sepsis and septic shock suffer from
altered innate and adaptive immune responses, leading to an impaired clearance of …

The pathophysiology of sepsis is not completely understood. Bacteria are the main cause of
sepsis. Activated receptors of the innate immune system lead to an exaggerated immune …