Hyperkalemia with RAAS inhibition: mechanism, clinical significance, and management

GL Hundemer, MM Sood - Pharmacological research, 2021 - Elsevier
Renin-angiotensin-aldosterone system (RAAS) inhibitors are evidence-based treatments for
a number of conditions including hypertension, diabetes mellitus, chronic kidney disease …

[HTML][HTML] Novel potassium binders: a clinical update

HT Wai, N Meah, R Katira - Br J Cardiol, 2021 - bjcardio.co.uk
Hyperkalaemia (HK) in heart failure and chronic kidney disease patients limits the use of
renin–angiotension–aldosterone system (RAAS) inhibitors, and successful intervention may …

Sodium zirconium cyclosilicate reconciles management of hyperkalemia and continuity of renin–angiotensin–aldosterone system inhibitors: a retrospective …

W Kimura, S Minatoguchi, T Mizuno, S Koide… - Journal of …, 2024 - Springer
Background Sodium zirconium cyclosilicate, a non-absorbed non-polymer zirconium
silicate, is a new potassium binder for hyperkalemia. A previous report showed that …

Pragmatic diagnostic and therapeutic algorithms to optimize new potassium binder use in cardiorenal disease

P Rossignol, J Silva-Cardoso, MN Kosiborod… - Pharmacological …, 2022 - Elsevier
Background Pivotal randomized trials demonstrating efficacy, safety and good tolerance, of
two new potassium binders (patiromer and sodium zirconium cyclosilicate) led to their recent …

[HTML][HTML] Hyperkalemia: Prevalence, predictors and emerging treatments

NL Larivée, JB Michaud, KM More, JA Wilson… - Cardiology and …, 2023 - Springer
It is well established that an elevated potassium level (hyperkalemia) is associated with a
risk of adverse events including morbidity, mortality and healthcare system cost …

[HTML][HTML] Patiromer induces rapid and sustained potassium lowering in patients with chronic kidney disease and hyperkalemia

DA Bushinsky, GH Williams, B Pitt, MR Weir… - Kidney international, 2015 - Elsevier
Patients with chronic kidney disease (CKD) have a high risk of hyperkalemia, which
increases mortality and can lead to renin–angiotensin–aldosterone system inhibitor (RAASi) …

[HTML][HTML] Recommendations for the management of hyperkalemia in patients receiving renin–angiotensin–aldosterone system inhibitors

L De Nicola, PM Ferraro, A Montagnani… - Internal and Emergency …, 2024 - Springer
Hyperkalemia is common in clinical practice and can be caused by medications used to treat
cardiovascular diseases, particularly renin–angiotensin–aldosterone system inhibitors …

Role of hyperkalemia in heart failure and the therapeutic use of potassium binders

CMS Sarwar, AA Bhagat, SD Anker, J Butler - Heart Failure, 2017 - Springer
Hyperkalemia can be a life-threatening disorder, especially for at-risk patients with heart
failure, chronic kidney disease, with diabetes, and patients on certain drugs like renin …

[HTML][HTML] Potassium-binding agents for the clinical management of hyperkalemia

M Chaitman, D Dixit, MB Bridgeman - Pharmacy and Therapeutics, 2016 - ncbi.nlm.nih.gov
Potassium-Binding Agents for the Clinical Management of Hyperkalemia - PMC Back to Top
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In pursuit of balance: renin–angiotensin–aldosterone system inhibitors and hyperkalaemia treatment

E Sciatti, E D'Elia, G Balestrieri, S D'Isa… - European Heart …, 2023 - academic.oup.com
Hyperkalaemia is a life-threatening condition leading to significant morbidity and mortality. It
is common in heart failure (HF) patients due to the disease itself, which often co-exists with …