Activation of the rat hypothalamic supramammillary nucleus by food anticipation, food restriction or ghrelin administration

MV Le May, C Hume, N Sabatier… - Journal of …, 2019 - Wiley Online Library
The circulating orexigenic hormone ghrelin targets many brain areas involved in feeding
control and signals via a dedicated receptor, the growth hormone secretagogue receptor 1A …

Divergent neuronal circuitries underlying acute orexigenic effects of peripheral or central ghrelin: critical role of brain accessibility

A Cabral, S Valdivia, G Fernandez… - Journal of …, 2014 - Wiley Online Library
Ghrelin is an octanoylated peptide hormone that potently and rapidly increases food intake.
The orexigenic action of ghrelin involves the hypothalamic arcuate nucleus (ARC), which is …

Rapid changes in the sensitivity of arcuate nucleus neurons to central ghrelin in relation to feeding status

V Scott, DM McDade, SM Luckman - Physiology & behavior, 2007 - Elsevier
Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor,
stimulates feeding and increases body weight. Systemic ghrelin administration induces the …

Growth hormone secretagogue receptor signaling in the supramammillary nucleus targets nitric oxide-producing neurons and controls recognition memory in mice

JP Aguggia, MP Cornejo, G Fernandez… - …, 2022 - Elsevier
Ghrelin is a stomach-derived hormone that acts via the growth hormone secretagogue
receptor (GHSR). Recent evidence suggests that some of ghrelin's actions may be mediated …

Circulating ghrelin acts on GABA neurons of the area postrema and mediates gastric emptying in male mice

A Cabral, MP Cornejo, G Fernandez… - …, 2017 - academic.oup.com
Ghrelin is known to act on the area postrema (AP), a sensory circumventricular organ
located in the medulla oblongata that regulates a variety of important physiological …

Ghrelin is an orexigenic and metabolic signaling peptide in the arcuate and paraventricular nuclei

PJ Currie, A Mirza, R Fuld, D Park… - American Journal of …, 2005 - journals.physiology.org
Ghrelin is a 28-amino acid acylated peptide and is the endogenous ligand for the growth
hormone secretagogue receptor (GHS-R). The GHS-R is expressed in hypothalamic nuclei …

Ghrelin and dopamine: new insights on the peripheral regulation of appetite

A Abizaid - Journal of neuroendocrinology, 2009 - Wiley Online Library
A review is provided of current evidence supporting the actions of the stomach‐derived
peptide ghrelin on ventral tegmental area (VTA) dopamine cells to increase food intake and …

The rat arcuate nucleus integrates peripheral signals provided by leptin, insulin, and a ghrelin mimetic

AK Hewson, LYC Tung, DW Connell, L Tookman… - Diabetes, 2002 - Am Diabetes Assoc
The hypothalamic circuits controlling food intake and body weight receive and integrate
information from circulating satiety signals such as leptin and insulin and also from ghrelin …

Ghrelin potentiates miniature excitatory postsynaptic currents in supraoptic magnocellular neurones

T Yokoyama, T Saito, T Ohbuchi… - Journal of …, 2009 - Wiley Online Library
Ghrelin is an orexigenic peptide discovered in the stomach as a ligand of the orphan G‐
protein coupled receptor, and participates in the regulation of growth hormone (GH) release …

The amygdala as a neurobiological target for ghrelin in rats: neuroanatomical, electrophysiological and behavioral evidence

M Alvarez-Crespo, KP Skibicka, I Farkas, CS Molnár… - 2012 - journals.plos.org
Here, we sought to demonstrate that the orexigenic circulating hormone, ghrelin, is able to
exert neurobiological effects (including those linked to feeding control) at the level of the …