[HTML][HTML] Mesenchymal stem cell-derived apoptotic bodies: biological functions and therapeutic potential

H Tang, H Luo, Z Zhang, D Yang - Cells, 2022 - mdpi.com
Mesenchymal stem cells (MSCs) are non-hematopoietic progenitor cells with self-renewal
ability and multipotency of osteogenic, chondrogenic, and adipogenic differentiation. MSCs …

[HTML][HTML] Emerging understanding of apoptosis in mediating mesenchymal stem cell therapy

Y Fu, B Sui, L Xiang, X Yan, D Wu, S Shi, X Hu - Cell Death & Disease, 2021 - nature.com
Mesenchymal stem cell transplantation (MSCT) has been recognized as a potent and
promising approach to achieve immunomodulation and tissue regeneration, but the …

[HTML][HTML] Apoptotic MSCs and MSC-derived apoptotic bodies as new therapeutic tools

IV Kholodenko, RV Kholodenko, AG Majouga… - Current Issues in …, 2022 - mdpi.com
Over the past two decades, mesenchymal stem cells (MSCs) have shown promising
therapeutic effects both in preclinical studies (in animal models of a wide range of diseases) …

[HTML][HTML] Immunomodulatory function of licensed human bone marrow mesenchymal stromal cell-derived apoptotic bodies

J Wang, E Donohoe, A Canning… - International …, 2023 - Elsevier
Abstract Background Mesenchymal stromal cells (MSCs) show great potential for
immunomodulatory and anti-inflammatory treatments. Clinical trials have been performed for …

Mesenchymal stem cells-derived apoptotic extracellular vesicles (ApoEVs): mechanism and application in tissue regeneration

Y Zhu, X Chen, Y Liao - Stem Cells, 2023 - academic.oup.com
Mesenchymal stem cells (MSCs) are commonly used as a source for cellular therapy owing
to their strong immunosuppressive and regenerative effects. However, MSCs undergo …

Apoptotic Vesicles of MSCs: The Natural Therapeutic Agents and Bio‐Vehicles for Targeting Drug Delivery

R Lin, T Zhang, J Gao - Small, 2023 - Wiley Online Library
Mesenchymal stem cell (MSC)‐based therapies are increasingly recognized as promising
cellular therapeutics and show the ability to treat various diseases. However, the underlying …

[HTML][HTML] Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages

J Liu, X Qiu, Y Lv, C Zheng, Y Dong, G Dou… - Stem cell research & …, 2020 - Springer
Background As the major interface between the body and the external environment, the skin
is liable to various injuries. Skin injuries often lead to severe disability, and the exploration of …

[HTML][HTML] The role of mesenchymal stem cell-derived extracellular vesicles in inflammation-associated programmed cell death

L Wang, Y Wu, R Yao, Y Li, Y Wei, Y Cao, Z Zhang… - Nano Today, 2023 - Elsevier
Mesenchymal stem cells (MSCs), as a kind of pluripotent adult stem cell capable of
exhibiting immunomodulatory properties, have been extensively studied in basic scientific …

[HTML][HTML] The critical role of apoptosis in mesenchymal stromal cell therapeutics and implications in homeostasis and normal tissue repair

C Giacomini, C Granéli, R Hicks, F Dazzi - Cellular & Molecular …, 2023 - nature.com
Mesenchymal stromal cells (MSCs) have been extensively tested for the treatment of
numerous clinical conditions and have demonstrated good safety but mixed efficacy …

[HTML][HTML] Generation of mesenchymal stem-like cells for producing extracellular vesicles

S Kim, TM Kim - World journal of stem cells, 2019 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are multipotent progenitor cells with therapeutic potential
against autoimmune diseases, inflammation, ischemia, and metabolic disorders. Contrary to …