Total sleep deprivation (TSD) for one whole night improves depressive symptoms in 40–
60% of treatments. The degree of clinical change spans a continuum from complete …

Objective To systematically review evidence on the efficacy and safety of sleep deprivation
(SD) as a treatment option for patients with unipolar or bipolar depression. Methods A …

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Total sleep deprivation (TSD) leads to an immediate amelioration of depressed mood in
approximately 70% of patients with the melancholic subtype of depression. The clinical utility …

Objective: The authors' goal was to test the hypothesis that the antidepressant effect of total
sleep deprivation can be maintained by initially avoiding sleep during a supposedly “critical” …

Growing clinical evidence in support of the efficacy and safety of sleep deprivation (SD), and
its biological mechanisms of action suggest that this technique can now be included among …

The antidepressant response to partial sleep deprivation early in the night (PSD‐E) was
compared with the response to partial sleep deprivation late in the night (PSD‐L) in 16 drug …

Sleep deprivation (SD) is a powerful antidepressant treatment that shows antidepressant
responses within hours in 40–60% of depressed patients. In more than 80% of responders …

This review reports, with as much detail as possible, on the literature relating to therapeutic
sleep deprivation (or induced-wakefulness therapy) since it was first described in 1971. The …

Sleep disturbance is a modifiable risk factor in the development and maintenance of
depression. In the context of current depression, although the data is mixed, some evidence …