Chimerism and clinical outcomes of 110 recipients of unrelated donor bone marrow transplants who underwent conditioning with low-dose, single-exposure total body …

M Girgis, C Hallemeier, W Blum, R Brown, H Lin… - Blood, 2005 - ashpublications.org
We hypothesized that low-dose (550-cGy), single-exposure, high dose rate (30 cGy/min)
total body irradiation (TBI) with cyclophosphamide as conditioning for HLA-compatible …

[PDF][PDF] Chimerism and clinical outcomes of 110 unrelated donor bone marrow transplant recipients conditioned with low dose (550 cGy), single exposure total body …

M Girgis, C Hallemeier, W Blum, R Brown, HS Lin… - Blood, 2004 - researchgate.net
We hypothesized that low dose (550 cGy), single exposure, high dose rate (30 cGy/min) total
body irradiation (TBI) with cyclophosphamide as conditioning for HLA compatible unrelated …

Low-dose total body irradiation (TBI) and fludarabine followed by hematopoietic cell transplantation (HCT) from HLA-matched or mismatched unrelated donors and …

D Niederwieser, M Maris, JA Shizuru… - Blood, The Journal …, 2003 - ashpublications.org
Toxicities of high-dose conditioning regimens have limited the use of conventional unrelated
donor hematopoietic cell transplantation (HCT) to younger, medically fit patients. Based on …

Low-dose (550 cGy), single-exposure total body irradiation and cyclophosphamide: consistent, durable engraftment of related-donor peripheral blood stem cells with …

W Blum, R Brown, HS Lin, B Zehnbauer… - Biology of Blood and …, 2002 - tctjournal.org
On the basis of observations of dog models and from earlier studies with humans, we
hypothesized that a lowdose (550 cGy) TBI-based conditioning regimen would result in …

Intentional induction of mixed chimerism and achievement of antitumor responses after nonmyeloablative conditioning therapy and HLA-matched donor bone marrow …

TR Spitzer, S McAfee, R Sackstein, C Colby… - Biology of Blood and …, 2000 - Elsevier
Mixed lymphohematopoietic chimerism can be induced in mice with bone marrow
transplantation (BMT) after a nonmyeloablative preparative regimen that includes …

Incidence of mixed chimaerism and clinical outcome in 101 patients after myeloablative conditioning regimens and allogeneic stem cell transplantation

R Wäsch, H Bertz, R Kunzmann… - British journal of …, 2000 - Wiley Online Library
In the light of reduced intensity conditioning regimens for allogeneic transplantation,
monitoring of donor cell engraftment acquires new relevance. We analysed the clinical …

Reduced intensity conditioning and prophylactic DLI can cure patients with high-risk acute leukaemias if complete donor chimerism can be achieved

G Massenkeil, M Nagy, M Lawang, O Rosen… - Bone marrow …, 2003 - nature.com
23 patients with ALL (n= 9) and AML (n= 14) underwent nonmyeloablative stem cell
transplantation (NST) from an HLA-identical donor after conditioning with fludarabine (180 …

[HTML][HTML] Low-dose total-body irradiation and fludarabine followed by hematopoietic cell transplantation from HLA-identical sibling donors do not induce complete T …

F Fernández-Avilés, A Urbano-Ispizua… - Experimental …, 2003 - Elsevier
OBJECTIVE: The aim of this study was to determine whether nonmyeloablative transplants
(NMT) result in complete and sustained donor engraftment in patients with progressive …

[HTML][HTML] Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced …

BR Dey, S McAfee, C Colby, R Sackstein… - Biology of Blood and …, 2003 - Elsevier
In an attempt to capture graft-versus-tumor effects without graft-versus-host disease (GVHD),
the authors initiated a trial of nonmyeloablative allogeneic bone marrow transplantation …

Anti‐tumour response despite loss of donor chimaerism in patients treated with non‐myeloablative conditioning and allogeneic stem cell transplantation

BR Dey, S McAfee, C Colby, K Cieply… - British journal of …, 2005 - Wiley Online Library
Based on a murine model, we conducted a series of trials of m‐myeloablative human
leucocyte antigen (HLA)‐matched or mismatched related donor stem cell transplantation …