[HTML][HTML] Prognostic value of vascular endothelial growth factor expression in patients with lung cancer: a systematic review with meta-analysis

P Zhan, J Wang, X Lv, Q Wang, L Qiu, X Lin… - Journal of Thoracic …, 2009 - Elsevier
Background Vascular endothelial growth factor (VEGF) has been implicated in
tumorigenesis and metastasis, and it presumably mediates the proliferation of endothelial …

Vascular endothelial growth factor A and vascular endothelial growth factor receptor 2 expression in non-small cell lung cancer patients: relation to prognosis

B Bonnesen, H Pappot, J Holmstav, BG Skov - Lung Cancer, 2009 - Elsevier
BACKGROUND: The majority of patients with non-small cell lung cancer (NSCLC) are
diagnosed with advanced inoperable disease. While treatment with conventional …

Prognostic significance of the expression of vascular endothelial growth factors A, B, C, and D and their receptors R1, R2, and R3 in patients with nonsmall cell lung …

E Carrillo de Santa Pau, FC Arias, E Caso Pelaez… - Cancer, 2009 - Wiley Online Library
BACKGROUND: Lung cancer is the leading cause of cancer death in the world. The
objective of this study was to investigate the expression of vascular endothelial growth …

Prognostic value of vascularity and vascular endothelial growth factor expression in non-small cell lung cancer

R Baillie, J Carlile, N Pendleton… - Journal of clinical …, 2001 - jcp.bmj.com
Aims—High expression of the angiogenic factor vascular endothelial growth factor (VEGF) in
tumours has been found to be associated with poor prognosis in some studies, but not in …

Expression of tumor-derived vascular endothelial growth factor and its receptors is associated with outcome in early squamous cell carcinoma of the lung

MJ Pajares, J Agorreta, M Larrayoz, A Vesin… - Journal of clinical …, 2012 - ascopubs.org
Purpose Antiangiogenic therapies targeting the vascular endothelial growth factor (VEGF)
pathway have yielded more modest clinical benefit to patients with non–small-cell lung …

VEGF and survival of patients with lung cancer: a systematic literature review and meta-analysis

P Delmotte, B Martin, M Paesmans… - Revue des maladies …, 2002 - europepmc.org
The process of angiogenesis is an important factor in tumour development. One of the
principal factors implicated in this process is vascular endothelial growth factor (VEGF) …

Expression of vascular endothelial growth factor (VEGF) in non-small cell lung cancer (NSCLC): association with p53 gene mutation and prognosis

W Niklińska, T Burzykowski, L Chyczewski, J Nikliński - Lung cancer, 2001 - Elsevier
Vascular endothelial growth factor (VEGF) is a multifunctional cytokine that increases
microvascular permeability and directly stimulates endothelial cell growth and angiogenesis …

Prognostic value of expression of vascular endothelial growth factor and its flt-1 and KDR receptors in stage I non-small-cell lung cancer

T Seto, M Higashiyama, H Funai, F Imamura… - Lung cancer, 2006 - Elsevier
BACKGROUND: Angiogenesis plays an important role in tumorigenesis and has attracted
interest as a potential target in cancer treatment. PATIENTS AND METHODS: We examined …

[HTML][HTML] Tumor cell expression of vascular endothelial growth factor receptor 2 is an adverse prognostic factor in patients with squamous cell carcinoma of the lung

TR Holzer, AD Fulford, DM Nedderman, TS Umberger… - PloS one, 2013 - journals.plos.org
A robust immunohistochemical (IHC) assay for VEGFR2 was developed to investigate its
utility for patient tailoring in clinical trials. The sensitivity, specificity, and selectivity of the IHC …

Vascular endothelial growth factor is associated with neovascularization and influences progression of non-small cell lung carcinoma.

G Fontanini, S Vignati, L Boldrini, S Chine… - Clinical cancer research …, 1997 - AACR
Vascular endothelial growth factor (VEGF) plays a pivotal role in the development of
neovascularization in both physiological and pathological processes, eg, developmental …