Transplants of adrenal medullary tissue or isolated chromaffin cells into the spinal cord
subarachnoid space has been shown to reduce pain sensitivity in rats. This analgesia …

Recent work in our laboratory has demonstrated that the transplantation of adrenal
medullary tissue into the spinal cord subarachnoid space can reduce pain sensitivity …

Adrenal chromaffin cells contain and release several neuroactive substances which induce
analgesia when injected directly into the spinal cord (eg opioid peptides and …

Adrenal medullary transplants in the spinal subarachnoid space may be a means of
achieving sustained local delivery of pain-reducing neuroactive substances on a continually …

Abstract Treatment of intractable pain with parenteral, subarachnoid, or epidural narcotics is
often unsatisfactory due to tolerance and other systemic complications that accompany …

Previous reports have indicated that the implantation of adrenal medullary chromaffin cells
into the spinal subarachnoid space can reduce both acute and chronic pain in several …

This study was undertaken to investigate the effects induced by the systemic administration
of RB 101 [N-{(R, S)-2-benzyl-3 [(S)(2-amino-4-methylthio) butyl dithio]-1-oxoprpyl}-l …

Previous work in this laboratory has shown that adrenal medullary transplants into the spinal
cord subarachnoid space can reduce pain sensitivity. This analgesia most likely results from …

Adrenal medullary transplants in the spinal subarachnoid space, by providing a continual
source of opioid peptides and catecholamines, offer a potentially important adjunct in the …

Adrenal medullary chromaffin cells were transplanted to the midbrain periaqueductal gray, a
region known to play a primary role in the modulation of nociception. Chromaffin cells were …