[HTML][HTML] Advantages of the avian model for human ovarian cancer

ADM Bernardo, S Thorsteinsdottir… - Molecular and clinical …, 2015 - ncbi.nlm.nih.gov
Ovarian cancer (OC) is the most lethal gynecological cancer. Early detection of OC is crucial
for providing efficient treatment, whereas high mortality rates correlate with late detection of …

[HTML][HTML] Mouse models of epithelial ovarian cancer for preclinical studies

S Karakashev, RG Zhang - Zoological research, 2021 - ncbi.nlm.nih.gov
Epithelial ovarian cancer (EOC) is the leading cause of gynecological cancer-related
mortality in the developed world. EOC is a heterogeneous disease represented by several …

Genetically‐defined ovarian cancer mouse models

PJ Morin, AT Weeraratna - The Journal of pathology, 2016 - Wiley Online Library
Epithelial ovarian cancer (EOC), the deadliest of gynaecological cancers, is a disease that
remains difficult to detect early and treat efficiently. A significant challenge for researchers in …

Characteristics of in vivo model systems for ovarian cancer studies

P Tudrej, KA Kujawa, AJ Cortez, KM Lisowska - Diagnostics, 2019 - mdpi.com
An understanding of the molecular pathogenesis and heterogeneity of ovarian cancer holds
promise for the development of early detection strategies and novel, efficient therapies. In …

Animal models of ovarian cancer

DC Connolly - Ovarian Cancer: Second Edition, 2010 - Springer
As contributors have discussed in previous chapters, our understanding of epithelial ovarian
cancer (EOC) biology and clinical management of ovarian cancer patients has improved …

Translational research in ovarian cancer: a must

TC Hamilton, DC Connolly, AY Nikitin… - International Journal of …, 2003 - ijgc.bmj.com
Ovarian cancer discovered at late clinical stage continues to be a fatal disease. It seems self-
evident that if we are to make an impact on the survival of advanced ovarian cancer patients …

Animal models of ovarian cancer

BC Vanderhyden, TJ Shaw, JF Ethier - Reproductive Biology and …, 2003 - Springer
Ovarian cancer is the most lethal of all of the gynecological cancers and can arise from any
cell type of the ovary, including germ cells, granulosa or stromal cells. However, the majority …

Recent technological advances in using mouse models to study ovarian cancer

CD House, L Hernandez, CM Annunziata - Frontiers in oncology, 2014 - frontiersin.org
Serous epithelial ovarian cancer (SEOC) is the most lethal gynecological cancer in the
United States with disease recurrence being the major cause of morbidity and mortality …

Histopathology of ovarian tumors in laying hens: a preclinical model of human ovarian cancer

A Barua, P Bitterman, JS Abramowicz… - International Journal of …, 2009 - ijgc.bmj.com
The high mortality rate due to ovarian cancer (OVCA) is attributed to the lack of an effective
early detection method. Because of the nonspecificity of symptoms at early stage, most of the …

[HTML][HTML] Ovarian cancer: pathology, biology, and disease models

DG Rosen, G Yang, G Liu, I Mercado-Uribe… - … in bioscience: a …, 2009 - ncbi.nlm.nih.gov
Epithelial ovarian cancer, which comprises several histologic types and grades, is the most
lethal cancer among women in the United States. In this review, we summarize recent …