Hypoxia-induced acute mountain sickness is associated with intracellular cerebral edema: a 3 T magnetic resonance imaging study

GG Schoonman, PS Sándor… - Journal of Cerebral …, 2008 - journals.sagepub.com
Acute mountain sickness is common among not acclimatized persons ascending to high
altitude; the underlying mechanism is unknown, but may be related to cerebral edema. Nine …

Magnetic resonance imaging evidence of cytotoxic cerebral edema in acute mountain sickness

K Kallenberg, DM Bailey, S Christ… - Journal of Cerebral …, 2007 - journals.sagepub.com
The present study applied T2-and diffusion-weighted magnetic resonance imaging to
examine if mild cerebral edema and subsequent brain swelling are implicated in the …

Normobaric hypoxia and symptoms of acute mountain sickness: elevated brain volume and intracranial hypertension

JS Lawley, N Alperin, AM Bagci, SH Lee… - Annals of …, 2014 - Wiley Online Library
Objective The study was undertaken to determine whether normobaric hypoxia causes
elevated brain volume and intracranial pressure in individuals with symptoms consistent …

Early brain swelling in acute hypoxia

DJ Dubowitz, EAW Dyer… - Journal of Applied …, 2009 - journals.physiology.org
Acute mountain sickness (AMS) and high-altitude cerebral edema share common clinical
characteristics, suggesting cerebral swelling may be an important factor in the …

Regional cerebral blood flow during acute hypoxia in individuals susceptible to acute mountain sickness

EAW Dyer, SR Hopkins, JE Perthen, RB Buxton… - Respiratory physiology …, 2008 - Elsevier
Individuals susceptible to high altitude pulmonary edema show altered pulmonary vascular
responses within minutes of exposure to hypoxia. We hypothesized that a similar acute …

Magnetic resonance investigation into the mechanisms involved in the development of high-altitude cerebral edema

RS Sagoo, CE Hutchinson, A Wright… - Journal of Cerebral …, 2017 - journals.sagepub.com
Rapid ascent to high altitude commonly results in acute mountain sickness, and on occasion
potentially fatal high-altitude cerebral edema. The exact pathophysiological mechanisms …

High-altitude cerebral edema evaluated with magnetic resonance imaging: clinical correlation and pathophysiology

PH Hackett, PR Yarnell, R Hill, K Reynard, J Heit… - Jama, 1998 - jamanetwork.com
Context.—Because of its onset in generally remote environments, high-altitude cerebral
edema (HACE) has received little scientific attention. Understanding the pathophysiology …

High-altitude cerebral edema: its own entity or end-stage acute mountain sickness?

REF Turner, H Gatterer, M Falla… - Journal of Applied …, 2021 - journals.physiology.org
High-altitude cerebral edema (HACE) and acute mountain sickness (AMS) are
neuropathologies associated with rapid exposure to hypoxia. However, speculation remains …

Sustained high-altitude hypoxia increases cerebral oxygen metabolism

ZM Smith, E Krizay, J Guo, DD Shin… - Journal of Applied …, 2013 - journals.physiology.org
Acute mountain sickness (AMS) is a common condition occurring within hours of rapid
exposure to high altitude. Despite its frequent occurrence, the pathophysiological …

Cerebral Diffusion and T2: MRI Predictors of Acute Mountain Sickness during Sustained High-Altitude Hypoxia

JS Hunt Jr, RJ Theilmann, ZM Smith… - Journal of Cerebral …, 2013 - journals.sagepub.com
Diffusion magnetic resonance imaging (MRI) provides a sensitive indicator of cerebral
hypoxia. We investigated if apparent diffusion coefficient (ADC) and transverse relaxation …