Genome-wide analysis of anorexia nervosa and major psychiatric disorders and related traits reveals genetic overlap and identifies novel risk loci for anorexia …
Anorexia nervosa (AN) is a heritable eating disorder (50–60%) with an array of commonly
comorbid psychiatric disorders and related traits. Although significant genetic correlations …
comorbid psychiatric disorders and related traits. Although significant genetic correlations …
Bridging the gap: Short structural variants in the genetics of anorexia nervosa
N Berthold, J Pytte, CM Bulik… - … Journal of Eating …, 2022 - Wiley Online Library
Anorexia nervosa (AN) is a devastating disorder with evidence of underexplored heritability.
Twin and family studies estimate heritability (h 2) to be 57%–64%, and genome‐wide …
Twin and family studies estimate heritability (h 2) to be 57%–64%, and genome‐wide …
[HTML][HTML] Genome-wide association study reveals first locus for anorexia nervosa and metabolic correlations
L Duncan, Z Yilmaz, R Walters, J Goldstein… - The American journal …, 2017 - ncbi.nlm.nih.gov
Objective To conduct a genome-wide association study (GWAS) of anorexia nervosa and to
calculate genetic correlations with a series of psychiatric, educational, and metabolic …
calculate genetic correlations with a series of psychiatric, educational, and metabolic …
Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa
LM Huckins, K Hatzikotoulas, L Southam… - Molecular …, 2018 - nature.com
Anorexia nervosa (AN) is a complex neuropsychiatric disorder presenting with dangerously
low body weight, and a deep and persistent fear of gaining weight. To date, only one …
low body weight, and a deep and persistent fear of gaining weight. To date, only one …
Brain-based gene expression of putative risk genes for anorexia nervosa
The etiology of anorexia nervosa (AN) remains elusive. Recent genome-wide association
studies identified the first genes liked to AN which reached genome-wide significance …
studies identified the first genes liked to AN which reached genome-wide significance …
Examination of the shared genetic basis of anorexia nervosa and obsessive–compulsive disorder
Z Yilmaz, M Halvorsen, J Bryois, D Yu… - Molecular …, 2020 - nature.com
Anorexia nervosa (AN) and obsessive–compulsive disorder (OCD) are often comorbid and
likely to share genetic risk factors. Hence, we examine their shared genetic background …
likely to share genetic risk factors. Hence, we examine their shared genetic background …
Overview of genetic research in anorexia nervosa: The past, the present and the future
MK Brandys, CGF de Kovel, MJ Kas… - … journal of eating …, 2015 - Wiley Online Library
Background Even though the evidence supporting the presence of a heritable component in
the aetiology of anorexia nervosa (AN) is strong, the underlying genetic mechanisms remain …
the aetiology of anorexia nervosa (AN) is strong, the underlying genetic mechanisms remain …
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness, affecting 0.9–4% of women and 0.3% of men,–, with twin-based heritability …
serious illness, affecting 0.9–4% of women and 0.3% of men,–, with twin-based heritability …
A genome-wide association study of anorexia nervosa
V Boraska, CS Franklin, JAB Floyd, LM Thornton… - Molecular …, 2014 - nature.com
Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by
dangerously low body weight. Neither candidate gene studies nor an initial genome-wide …
dangerously low body weight. Neither candidate gene studies nor an initial genome-wide …
Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa
Objective: The authors conducted a genome-wide association study of anorexia nervosa
and calculated genetic correlations with a series of psychiatric, educational, and metabolic …
and calculated genetic correlations with a series of psychiatric, educational, and metabolic …