Congenital hypothyroidism (CH) is the most common congenital endocrine disorder. The
early treatment of CH patients has successfully improved the prognosis and management of …

Subclinical hypothyroidism is defined as serum levels of TSH above the upper limit of the
reference range, in the presence of normal concentrations of total T4 or free T4. This …

Although early treatment of congenital hypothyroidism leads to improved outcome, minor
deficits may arise from insufficient thyroid hormone before birth and during infancy. It is …

Context: Little is known about the long-term health of patients treated for congenital
hypothyroidism since the neonatal period. Objective: To evaluate the causes of mortality and …

Background: Thyroid hormone (T3) is essential for normal development of children enabling
brain development and somatic growth. However, certain individuals are genetically …

Mild hypothyroidism, also known as subclinical hypothyroidism (SH), is biochemically
defined as serum TSH levels above the upper limit of the reference range, in the presence of …

Objective: The aim was to formulate practice guidelines for the diagnosis and management
of congenital hypothyroidism (CH). Evidence: A systematic literature search was conducted …

The introduction of neonatal screening for congenital hypothyroidism (CH) has had a
dramatic effect on the prognosis of affected children. Thyroxine is essential for neurological …

Objective Subclinical hypothyroidism (SH) is quite common in children and adolescents. The
natural history of this condition and the potential effects of replacement therapy need to be …

Thyroid hormone has important physiologic functions in nearly every organ system. The
critical role of thyroid hormone in growth and in physical and neurologic development lends …