Retinoids are ubiquitous signaling molecules that influence nearly every cell type, exert
profound effects on development, and complement cancer chemotherapeutic regimens. All …

Vitamin A (all-trans retinol) and its active metabolites, collectively called retinoids, exert
potent effects on stem cell differentiation and thus, the formation of the entire organism, in …

Retinoids (ie, vitamin A, all-trans retinoic acid, and related signaling molecules) induce the
differentiation of various types of stem cells. Nuclear retinoic acid receptors mediate most but …

Retinoids comprise a group of compounds each composed of three basic parts: a
trimethylated cyclohexene ring that is a bulky hydrophobic group, a conjugated tetraene side …

Retinoic acid (RA), the major bioactive metabolite of retinol or vitamin A, induces a spectrum
of pleiotropic effects in cell growth and differentiation that are relevant for embryonic …

The retinoids are a class of compounds that are structurally related to vitamin A. Retinoic
acid, which is the active metabolite of retinol, regulates a wide range of biological processes …

Vitamin A (retinol), its natural and synthetic derivatives, and its metabolites are known
collectively as retinoids (Fig. 1). Vitamin A is required in the diets of vertebrate animals, and …

Retinoic acid (RA) agents possess anti-tumor activity through their ability to induce cellular
differentiation. However, retinoids have not yet been translated into effective systemic …

Retinoids (retinol [vitamin A] and its biologically active metabolites) are essential signaling
molecules that control various developmental pathways and influence the proliferation and …

Vitamin A serves as substrate for the biosynthesis of several derivates (retinoids) which are
important for cell growth and cell differentiation as well as for vision. Retinoic acid is the …