Background Exposure of human populations to ambient particulate matter (PM) air pollution
significantly contributes to the mortality attributable to ischemic cardiovascular events. We …

Acute exposure to particulate matter (PM) air pollution causes thrombotic cardiovascular
events, leading to increased mortality rates; however, the link between PM and …

The mechanisms by which exposure to particulate matter increases the risk of
cardiovascular events are not known. Recent human and animal data suggest that …

The biological mechanisms responsible for an association between elevated concentrations
of ambient particulate matter (PM) and increased cardiovascular morbidity and mortality …

While inflammation is often associated with increased Plasminogen Activator Inhibitor-1 (PAI-
1), the functional consequences of PAI-1 in inflammation have yet to be fully determined …

Plasminogen activator inhibitor-1 (PAI-1) plays a role in regulating levels of some cytokines
and cell migration in addition to its classic role in inhibiting fibrinolysis. PAI-1 levels in …

Epidemiological studies have linked levels of particulate matter (PM) in ambient air to
cardiovascular mortality and hospitalizations for myocardial infarction (MI) and stroke …

Parenchymal lung inflammation and airway and alveolar epithelial cell apoptosis are
associated with cigarette smoke exposure (CSE), which contributes to chronic obstructive …

Background: Epidemiological findings suggest an association between exposure to
particulate matter (PM) and venous thrombo‐embolism. Objectives: To investigate arterial …

Increasingly, evidence suggests a role for a systemic procoagulant state in the pathogenesis
of cardiac dysfunction subsequent to inhalation of airborne particulate matter. The authors …