This study is the first report of the solubilization of niclosamide by cyclodextrin complexation
or the interaction between the drug and polyamidoamine (PAMAM) dendrimers. Half …

The solubility of the hydrophobic drug ibuprofen has been compared in an aqueous solution
of polyamidoamine (PAMAM) G4 dendrimer and sodium dodecyl sulphate (SDS). The …

The aqueous solubility of non-steroidal anti-inflammatory drugs (NSAIDs) Ketoprofen,
Ibuprofen, Diflunisal and Naproxen were measured in the presence of the ethylenediamine …

In the present study we investigated the effect of ethylenediamine (EDA) core
polyamidoamine (PAMAM) dendrimers on the aqueous solubility of nicotinic acid. The …

The interactions between dendrimers and different types of drugs are nowadays one of the
most actively investigated areas of the pharmaceutical sciences. The interactions between …

A drug is effective in their molecular form; thus solubility in the biological fluid is important.
Pharmaceutical researchers are continuously working on the improvement of solubility of …

The solubility enhancement of 11 poorly soluble drugs by complexation using nicotinamide
has been studied. The solubilization efficiency of nicotinamide has been compared to that of …

The complexation of the practically insoluble drug furosemide (acidic pKa 3.22) with lower
generation PAMAM dendrimers showed a significant release dependence on the ionization …

Aims Aim of the study was to enhance the solubility of Chlorthalidone by developing beta-
cyclodextrin cross-linked hydrophilic nanomatrices. Main methods Nine different …

Dendrimers are 3D, hyperbranched, tree-like polymers having immense potential in drug
delivery, targeting, diagnosis and as carriers for DNA/gene delivery. Dendrimers have …