The biological response to signal activation depends on the ability of cells to integrate
concomitantly activated signaling pathways. At the molecular level, one of the best …

Background. Activating mutations of protein Gsa that stimulates adenylyl cyclase are present
in a subset of thyroid adenomas. Cholera loxin A1 subunit (C. T) mimics these mutations via …

While researching for this article, I became aware of the prevalence of this disease due to its
presence in two close relatives who were diagnosed a few years ago. Thankfully, both …

In toxic thyroid adenomas, mutations in the TSH receptor (TSH-R) gene or the gene
encoding the alpha-subunit of the stimulatory guanine nucleotide-binding protein (Gs alpha) …

44 Information Jpn. 1. Vet. Res. 49 (1),(2001) type 5a showed larger number of granulosa
cells, higher estradiol-17~ production and higher proportion of follicles with TGF-~ 1 positive …

Long non-coding RNAs (lncRNAs) play key regulatory roles in cancer progression and are
novel therapeutic targets1. We have discovered a lncRNA on the antisense strand of the …

OBJECTIVE Activation of ras proto‐oncogenes as a result of point mutations is detectable in
a significant percentage of most types of tumour. Similar to neoplasms of other organs …

The signaling pathways that govern the lactotrope-specific differentiated phenotype, and
those that control lactotrope proliferation in both physiological and pathological lactotrope …

The 4th edition of this highly successful textbook continues to have the same focus as
previous editions––the integrative and regulatory roles of the endocrine systems, with upto …