Receptor activator of NF-κB ligand (RANKL) and its receptor activator of NF-κB (RANK) play
pivotal roles in osteoclast differentiation and function. However, the structural determinants …

Receptor activator of NF-κB (RANK) ligand (RANKL) and its receptor RANK play an
essential role in osteoclastogenesis and osteoclast function by activating several signaling …

Receptor activator of NF-κB ligand (RANKL) plays a crucial role in osteoclast differentiation,
function, and survival. RANKL exerts its effect by activating its receptor RANK (receptor …

Receptor activator of NF-κB (RANK) activation by RANK ligand (RANKL) mediates
osteoclastogenesis by recruiting TNF receptor-associated factors (TRAFs) via three …

Tumor necrosis factor-α (TNF) enhances osteoclast formation and activity leading to bone
loss in various pathological conditions, but its precise role in osteoclastogenesis remains …

The receptor activator of nuclear factor-κB ligand (RANKL), a member of the tumor necrosis
factor family, is a transmembrane protein, which is known as an essential initiation factor of …

Receptor activator of nuclear factor-κB ligand [RANK ligand (RANK-L)] stimulates mature
osteoclasts to resorb bone, a process associated with NF-κB activation. RANK-L also …

The tumor necrosis factor (TNF)‐like core domain of receptor activator of nuclear factor‐κB
ligand (RANKL) is a functional domain critical for osteoclast differentiation. One of the …

A variety of humoral factors modulate the osteoclastogenesis. Receptor activator of NF-κB
ligand (RANKL) expressed on osteoblast/stromal lineage cells plays a pivotal role to …

A complementary DNA (cDNA) encoding the rat homologue of receptor activator of NF‐κB
ligand/osteoprotegerin ligand/osteoclast differentiation factor/tumor necrosis factor (TNF) …