Effect of tachykinin receptor inhibition in the brain on cardiovascular and behavioral responses to stress
J Culman, S Klee, C Ohlendorf, T Unger - Journal of Pharmacology and …, 1997 - ASPET
The neurokinins, substance P (SP) and neurokinin A (NKA) represent natural, nonspecific
ligands of NK1 and NK2receptors. In our study in conscious rats, we tested the hypothesis …
ligands of NK1 and NK2receptors. In our study in conscious rats, we tested the hypothesis …
Identification of the central tachykinin receptor subclass involved in substance P-induced cardiovascular and behavioral responses in conscious rats
K Ito, C Tschöpe, N Jost, J Culman, C Lebrun… - European journal of …, 1992 - Elsevier
To identify the tachykinin receptor subclass involved in the central cardiovascular and
behavioral actions of substance P (SP), we compared the central actions of SP with those of …
behavioral actions of substance P (SP), we compared the central actions of SP with those of …
Characterization of the tachykinin receptors involved in spinal and supraspinal cardiovascular regulation
R Couture, P Picard, P Poulat… - Canadian journal of …, 1995 - cdnsciencepub.com
The pharmacological characterization of the tachykinin receptors involved in spinal and
supraspinal cardiovascular regulation is reviewed in this report. In conscious rats, substance …
supraspinal cardiovascular regulation is reviewed in this report. In conscious rats, substance …
Effects of the tachykinin NK1 receptor antagonist, RP 67580, on central cardiovascular and behavioural effects of substance P, neurokinin A and neurokinin B
J Culman, B Wiegand, H Spitznagel… - British journal of …, 1995 - Wiley Online Library
1 We have investigated the effects of the non‐peptide NK1 tachykinin receptor antagonist,
RP 67580, and its inactive enantiomer, RP 68651, on the cardiovascular and behavioural …
RP 67580, and its inactive enantiomer, RP 68651, on the cardiovascular and behavioural …
Characterization of the peripheral action of neurokinins and neurokinin receptor selective agonists on the rat cardiovascular system
R Couture, O Laneuville, C Guimond… - Naunyn-Schmiedeberg's …, 1989 - Springer
The effects on mean arterial pressure (MAP) and heart rate (HR) of increasing doses (0.65–
65 nmol/kg) of substance P (SP), neurokinin A (NKA), neurokinin B (NKB) and selective …
65 nmol/kg) of substance P (SP), neurokinin A (NKA), neurokinin B (NKB) and selective …
Cardiovascular and behavioural effects of centrally administered tachykinins in the rat: characterization of receptors with selective antagonists
P Picard, D Regoli, R Couture - British journal of pharmacology, 1994 - Wiley Online Library
1 The effects of intracerebroventricular (icv) injection of selective and potent NK1 (RP
67580), NK2 (SR 48968) and NK3 (R 486,[Trp7, β‐Ala8] NKA (4–10)) receptor antagonists …
67580), NK2 (SR 48968) and NK3 (R 486,[Trp7, β‐Ala8] NKA (4–10)) receptor antagonists …
Use of selective antagonists to dissociate the central cardiovascular and behavioural effects of tachykinins on NK1 and NK2 receptors in the rat.
The effects of intracerebroventricular (icv) pretreatment with selective NK1 ((+/-)-CP 96,345),
NK2a (MEN 10,207; MEN 10,376) and NK2b (R 396) tachykinin receptor antagonists on the …
NK2a (MEN 10,207; MEN 10,376) and NK2b (R 396) tachykinin receptor antagonists on the …
Implication of nigral tachykinin NK3 receptors in the maintenance of hypertension in spontaneously hypertensive rats: a pharmacologic and autoradiographic study
A Lessard, MM Campos… - British journal of …, 2003 - Wiley Online Library
The role of nigral tachykinin NK1, NK2 and NK3 receptors in central cardiovascular
regulation was studied by measuring the effects of selective agonists and antagonists on …
regulation was studied by measuring the effects of selective agonists and antagonists on …
Spinal action of neurokinins producing cardiovascular responses in the conscious freely moving rat: evidence for a NK-1 receptor mechanism
H Hasséssian, G Drapeau, R Couture - Naunyn-Schmiedeberg's archives …, 1988 - Springer
This study was initiated to characterize the receptors which mediate the cardiovascular
responses elicited by the intrathecal (i. th.) administration of neurokinins (NK) in the …
responses elicited by the intrathecal (i. th.) administration of neurokinins (NK) in the …
C-FOS expression in the rat brain in response to substance P and neurokinin B
H Spitznagel, J Baulmann, A Blume, T Unger… - Brain research, 2001 - Elsevier
Substance P, the principal neurokinin peptide in the mammalian brain and the natural ligand
for the NK1 tachykinin receptor, plays an integrative role in the regulation of cardiovascular …
for the NK1 tachykinin receptor, plays an integrative role in the regulation of cardiovascular …
相关搜索
- cardiovascular and behavioral responses
- tachykinin receptors cardiovascular regulation
- tachykinin nk1 receptor antagonist
- central cardiovascular behavioural effects
- receptor mechanism cardiovascular responses
- central cardiovascular receptors in the rat
- behavioural effects receptors in the rat
- tachykinin nk3 receptors
- spinal action cardiovascular responses
- central cardiovascular selective antagonists
- behavioral responses conscious rats