Era of genomic medicine: a narrative review on CRISPR technology as a potential therapeutic tool for human diseases

OW Kotagama, CD Jayasinghe… - BioMed research …, 2019 - Wiley Online Library
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) provides acquired
immunity in microorganisms against exogenous DNA that may hinder the survival of the …

CRISPR-Cas9: A fascinating journey from bacterial immune system to human gene editing

MA Hossain - Progress in Molecular Biology and Translational …, 2021 - Elsevier
Abstract Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-Cas system
has been discovered as an adaptive-immune system in prokaryotes. Microbes like bacteria …

CRISPR/Cas based gene editing: marking a new era in medical science

K Prasad, A George, NS Ravi… - Molecular Biology Reports, 2021 - Springer
CRISPR/Cas9 system, a bacterial adaptive immune system developed into a genome
editing technology, has emerged as a powerful tool revolutionising genome engineering in …

[PDF][PDF] CRISPR/Cas9 technology in translational biomedicine

EI Leonova, RR Gainetdinov - Cell Physiol Biochem, 2020 - cellphysiolbiochem.com
Abstract The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-RNA-
guided Cas9 endonuclease system has provided a fast and efficient method for precise …

CRISPR/Cas9 therapeutics: progress and prospects

T Li, Y Yang, H Qi, W Cui, L Zhang, X Fu, X He… - … and Targeted Therapy, 2023 - nature.com
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated
protein 9 (Cas9) gene-editing technology is the ideal tool of the future for treating diseases …

[PDF][PDF] CRISPR technology: new paradigm to target the infectious disease pathogens.

MA Bakhrebah, MS Nassar… - European Review for …, 2018 - europeanreview.org
OBJECTIVE: Infectious diseases are one of the prime causes of death worldwide. An
innovative sequence specific editing technology “Clustered Regularly Interspaced Short …

CRISPR/Cas9: prospects and challenges

F Zhang - Human gene therapy, 2015 - ncbi.nlm.nih.gov
All science takes inspiration from nature, but nowhere is this more true than in biology,
where some of the most powerful tools available to researchers are derived from natural …

Progress and Perspective of CRISPR‐Cas9 Technology in Translational Medicine

R Zheng, L Zhang, R Parvin, L Su, J Chi… - Advanced …, 2023 - Wiley Online Library
Translational medicine aims to improve human health by exploring potential treatment
methods developed during basic scientific research and applying them to the treatment of …

An update on the application of CRISPR technology in clinical practice

F Morshedzadeh, M Ghanei, M Lotfi, M Ghasemi… - Molecular …, 2024 - Springer
The CRISPR/Cas system, an innovative gene-editing tool, is emerging as a promising
technique for genome modifications. This straightforward technique was created based on …

CRISPR-Cas9 gene editing: Delivery aspects and therapeutic potential

EO Blenke, MJW Evers, E Mastrobattista… - Journal of Controlled …, 2016 - Elsevier
The CRISPR-Cas9 gene editing system has taken the biomedical science field by storm,
initiating rumors about future Nobel Prizes and heating up a fierce patent war, but also …