Hyaluronan influences lung fluid balance. The clearance of lung hyaluronan by way of the
pulmonary lymphatics and the pleural space is increased when fluid flux into the interstitium …

Although lymphatic washout of hyaluronan during lung hydration has been postulated to
deplete lung interstitial hyaluronan content and thereby contribute to the decreased …

We have determined whether changes in lung hyaluronan content affect extravascular water
in lungs of unanesthetized rabbits. Three groups of experiments were performed. In group 1 …

The effects of increased hydrostatic pressure on the concentrations of hyaluronan
(hyaluronic acid) in lung lymph and serum were investigated in awake sheep with a cannula …

We developed a method that used Alcian blue bound to hyaluronan to measure pleural
hyaluronan in rabbits postmortem. Rabbits were killed, then ventilated with 21% O 2–5% CO …

Hyaluronan, an important constituent of developmental interstitium in fetal lungs, mediates
cell-to-cell interactions and thereby directs migrating cells. Furthermore, because of the …

This study was designed to define how hyaluronan (HA) is bound in lung tissue. Aliquots of
lyophilized hamster lungs were extracted with 0.5 M NaCl (associative conditions) or 4 M …

The hypothesis of this study is that pleural lubrication is enhanced by hyaluronan acting as a
boundary lubricant in pleural liquid and by pleural filtration as reflected in changes in protein …

The effect of septicemia on the elimination of hyaluronan (HA) from the lung interstitium was
investigated in awake sheep with chronic lung lymph and thoracic duct fistulas. The result …

The pulmonary interstitium may affect the movement of water, macromolecules, and
inflammatory cells between capillaries and lymphatics. Hyaluronan (hyaluronic acid), a …