The degree of acute improvement in spirometric indices after bronchodilator inhalation
varies among chronic obstructive pulmonary disease (COPD) patients, and depends upon …

Background Debate continues as to whether acute bronchodilator responsiveness (BDR)
predicts long-term outcomes in COPD. Furthermore, there is no consensus on a threshold …

Objective Bronchodilators are routinely used in the long-term therapy of patients with COPD.
These drugs are generally evaluated for their short-term bronchodilatory effects. Long-term …

Objectives: To determine whether long-term symptomatic improvement occurs in COPD
patients with maintenance bronchodilator therapy despite a nonsignificant short-term …

Background: Patients with symptoms of GOLD stage I chronic obstructive pulmonary disease
(COPD) can have significant abnormalities of ventilatory mechanics with greater exertional …

Partial bronchodilator reversibility can be demonstrated in many patients with stable chronic
obstructive pulmonary disease (COPD), but its relevance to exercise capacity and symptoms …

COPD is a preventable and treatable disease characterized by airflow limitation that is not
fully reversible. The diagnosis of COPD is based on spirometric evidence of airways …

Patients with COPD may respond differently to anticholinergic and beta-agonist
bronchodilators. Previously, in acutely ill COPD patients, we showed similar improvements …

BACKGROUND: Airway medications have not been shown to reduce the loss of lung
function in patients with COPD. We explored whether tiotropium 18μg once daily could slow …

BACKGROUND Bronchodilator reversibility testing is recommended in all patients with
chronic obstructive pulmonary disease (COPD) but does not predict improvements in …