Melatonin: highlighting its use as a potential treatment for SARS-CoV-2 infection

RJ Reiter, R Sharma, F Simko… - Cellular and Molecular …, 2022 - Springer
Numerous pharmaceutical drugs have been repurposed for use as treatments for COVID-19
disease. These drugs have not consistently demonstrated high efficacy in preventing or …

Possible application of melatonin in long COVID

DP Cardinali, GM Brown, SR Pandi-Perumal - Biomolecules, 2022 - mdpi.com
Clinical sequelae and symptoms for a considerable number of COVID-19 patients can linger
for months beyond the acute stage of SARS-CoV-2 infection,“long COVID”. Among the long …

[HTML][HTML] Therapeutic algorithm for use of melatonin in patients with COVID-19

RJ Reiter, P Abreu-Gonzalez, PE Marik… - Frontiers in …, 2020 - frontiersin.org
The coronavirus, COVID-19, has infected hundreds of thousands and killed tens of
thousands of individuals worldwide. This highly infectious condition continues to ravage the …

Mechanisms and clinical evidence to support melatonin's use in severe COVID-19 patients to lower mortality

DX Tan, RJ Reiter - Life Sciences, 2022 - Elsevier
The fear of SARS-CoV-2 infection is due to its high mortality related to seasonal flu. To date,
few medicines have been developed to significantly reduce the mortality of the severe …

COVID-19: Melatonin as a potential adjuvant treatment

R Zhang, X Wang, L Ni, X Di, B Ma, S Niu, C Liu… - Life sciences, 2020 - Elsevier
This article summarizes the likely benefits of melatonin in the attenuation of COVID-19
based on its putative pathogenesis. The recent outbreak of COVID-19 has become a …

Melatonin as a potential adjuvant treatment for COVID-19 beyond sleep disorders

A Wichniak, A Kania, M Siemiński… - International Journal of …, 2021 - mdpi.com
Melatonin is registered to treat circadian rhythm sleep–wake disorders and insomnia in
patients aged 55 years and over. The essential role of the circadian sleep rhythm in the …

[HTML][HTML] Protective effect of melatonin administration against SARS-CoV-2 infection: A systematic review

A Molina-Carballo, R Palacios-López… - Current Issues in …, 2022 - mdpi.com
Introduction: according to the World Health Organization (WHO), COVID-19 is an infectious
disease caused by the SARS-CoV-2 virus, responsible for an increasing number of cases …

Can melatonin reduce the severity of COVID-19 pandemic?

A Shneider, A Kudriavtsev… - International reviews of …, 2020 - Taylor & Francis
The current COVID-19 pandemic is one of the most devastating events in recent history. The
virus causes relatively minor damage to young, healthy populations, imposing life …

Clinical trials for use of melatonin to fight against COVID-19 are urgently needed

K Kleszczyński, AT Slominski, K Steinbrink, RJ Reiter - Nutrients, 2020 - mdpi.com
The recent pandemic of COVID-19 has already infected millions of individuals and has
resulted in the death of hundreds of thousands worldwide. Based on clinical features …

The coronavirus disease 2019 (COVID-19): key emphasis on melatonin safety and therapeutic efficacy

E Ramos, F Lopez-Munoz, E Gil-Martin, J Egea… - Antioxidants, 2021 - mdpi.com
Viral infections constitute a tectonic convulsion in the normophysiology of the hosts. The
current coronavirus disease 2019 (COVID-19) pandemic is not an exception, and therefore …