Efficient induction of anti-tumor immunity by a TAT-CEA fusion protein vaccine with poly (I: C) in a murine colorectal tumor model

JS Park, HS Kim, HM Park, CH Kim, TG Kim - Vaccine, 2011 - Elsevier
Protein vaccines may be a useful strategy for cancer immunotherapy because recombinant
tumor antigen proteins can be produced on a large scale at relatively low cost and have …

A multimeric carcinoembryonic antigen signal inhibits the activation of human T cells by a SHP‐independent mechanism: A potential mechanism for tumor‐mediated …

KA Lee, EA Bae, YC Song, EK Kim… - … journal of cancer, 2015 - Wiley Online Library
Carcinoembryonic antigen (CEA) is a well‐known tumor antigen that is found in the serum of
patients with various cancers and is correlated with an increased risk of cancer recurrence …

Induction of cytotoxic T cells and their antitumor activity in mice transgenic for carcinoembryonic antigen

S Mizobata, K Tompkins, JF Simpson, Y Shyr… - Cancer Immunology …, 2000 - Springer
In order to develop immunotherapy strategies that are based on eliciting immune
responsiveness to the self-antigen, human carcinoembryonic antigen (CEA), we examined …

Protective immunity against human carcinoembryonic antigen (CEA) induced by an oral DNA vaccine in CEA-transgenic mice

R Xiang, S Silletti, HN Lode, CS Dolman… - Clinical cancer …, 2001 - AACR
Peripheral T-cell tolerance toward human carcinoembryonic self-antigen (CEA) was broken
in CEA-transgenic C57BL/6J mice by an oral CEA-based DNA vaccine. This vaccine …

Immunotherapy of cancer: generation of CEA specific CTL using CEA peptide pulsed dendritic cells

SE Alters, JR Gadea, R Philip - Dendritic Cells in Fundamental and …, 1997 - Springer
Antigen specific cytotoxic T lymphocytes (CTL) are being studied for their potential
immunotherapeutic benefit in the treatment of cancer. Carcinoembryonic antigen (CEA) is an …

Efficient induction of anti-tumor immunity by a TAT-CEA fusion protein vaccine with poly (I: C) in a murine colorectal tumor model.

PJS Park JungSun, KHS Kim HyeSung… - 2011 - cabidigitallibrary.org
Protein vaccines may be a useful strategy for cancer immunotherapy because recombinant
tumor antigen proteins can be produced on a large scale at relatively low cost and have …

[引用][C] Session I: Translational research-DNA vaccines and immunocytokines for cancer therapy

R Reisfeld, R Xiang, U Pertl… - Cancer …, 2003 - Springer Science and Business …

Potent induction of B-and T-cell immunity against human carcinoembryonic antigen-expressing tumors in human carcinoembryonic antigen transgenic mice mediated …

S Loisel-Meyer, T Felizardo, J Mariotti… - Molecular cancer …, 2009 - AACR
The applicability of immunotherapy would be dramatically broadened to a greater number of
recipients if direct “off-the-shelf” products could be engineered to engender functionally …

Carcinoembryonic antigen as a target to induce anti-tumor immune responses

P Sarobe, E Huarte, JJ Lasarte… - Current cancer drug …, 2004 - ingentaconnect.com
Identification of relevant targets for cancer therapy is a major goal in cancer research. In this
field, the identification of tumor antigens has opened the possibility of inducing specific anti …

Epigenetic modulation of colorectal cancer cells for cancer-testis antigen-targeted immunotherapy

J Chou, LN Voong, X Chen, C Yee, EH Warren - Cancer Research, 2010 - AACR
Cancer-testis (CT) antigens represent attractive potential targets for cancer immunotherapy
due to their limited expression in normal somatic tissues and their widespread expression in …