The identification of genes and deduced pathways from the mature human oocyte can help
us better understand oogenesis, folliculogenesis, fertilization, and embryonic development …

The oocyte is a key regulator of ovarian folliculogenesis and early embryonic development.
However, the composition of the oocyte transcriptome and identities and functions of key …

The ability to identify oocytes with the greatest potential for producing a viable embryo would
be of great benefit to assisted reproductive treatments. One of the most important defects …

OBJECTIVE: The purpose of this study was to catalog genes expressed in human oocytes at
germinal vesicle (GV) or metaphase II (MII) stage and to compare gene profiles between …

Consecutive application of PCR and serial analysis of gene expression (SAGE) was used to
generate a catalog of∼ 50,000 SAGEtags from nine human oocytes. Matches for known …

BACKGROUND Immature human oocytes matured in vitro, particularly those from
gonadotrophin stimulated ovaries, are developmentally incompetent when compared with …

Various morphological and cytological traits of oocytes and their surrounding cumulus cells
may be used to select oocytes for assisted reproduction. However, even with careful …

The age-related decline in female fertility has been attributed to a variety of causes including
progressive oocyte depletion, meiotic irregularities and mitochondrial dysfunction. However …

As IVF becomes an increasingly popular method for human reproduction, it is more critical
than ever to understand the unique molecular composition of the mammalian oocyte. DNA …

Background Cumulus cells (CC) encapsulate growing oocytes and support their growth and
development. Transcriptomic signatures of CC have the potential to serve as valuable non …