The preservation of kidney grafts has historically been based on hypothermia of the organs
to decrease the baseline cellular metabolism. According to the Van't Hoff equation, during …

In the last 5 years, normothermic perfusion has been translated from an experimental
laboratory technique into clinical practice with promising results. Normothermic perfusion …

The increasing demand on donor grafts has forced experimental research on transplantation
medicine to develop more efficient organ preservation strategies. Simple cold storage of …

A great deal of research is still needed to optimize and logistically place hypothermic and
normothermic perfusion technologies. In the future, we may progress toward organ-tailored …

Kidney transplantation is limited by hypothermic preservation techniques. Prolonged periods
of cold ischaemia increase the risk of early graft dysfunction and reduce long‐term survival …

One of the main causes of early graft dysfunction in kidney transplantation is ischaemia
reperfusion (I/R) injury. This unavoidable event occurs immediately when oxygenated blood …

Normothermic machine perfusion (NMP) is emerging as a novel preservation strategy.
During NMP, the organ is maintained in a metabolically active state that may not only …

This chapter reviews the history and origin of ex vivo normothermic perfusion (EVNP)
techniques and their current application in renal transplantation. Much of technology used in …

Normothermic machine perfusion (NMP) is emerging as a novel preservation strategy.
During NMP, the organ is maintained in a metabolically active state that may not only …

In recent years, normothermic machine perfusion (NMP) has emerged in conversation
surrounding organ preservation and transplantation techniques with the goal of improving …