Background Myostatin (MSTN) is a key negative regulator of muscle mass in humans and
animals, having direct and indirect influences on molecular regulators of atrophy and …

Myostatin is a member of the transforming growth factor-beta/bone morphogenetic protein
(TGF-β/BMP) super-family of secreted factors that functions as a potent inhibitor of skeletal …

Myostatin is a negative regulator of muscle mass. Important advances in our understanding
of the complex biology of this factor have revealed the therapeutic potential of antagonizing …

Myostatin, a member of the transforming growth factor beta (TGF-β) superfamily, was first
described in 1997. Since then, myostatin has gained growing attention because of the …

Myostatin (Mstn) participates in the regulation of skeletal muscle size and has emerged as a
regulator of muscle metabolism. Here, we hypothesized that lack of myostatin profoundly …

Aim Some health benefits of exercise may be explained by an altered secretion of myokines.
Because previous focus has been on upregulated myokines, we screened for …

Myostatin is a negative regulator of skeletal muscle growth. Myostatin mutations and
pharmacological strategies increase muscle mass in vivo, suggesting that myostatin …

Myostatin is a member of the TGF-β superfamily that is essential for proper regulation of
skeletal muscle growth. As do other TGF-β superfamily members, myostatin signals into the …

Myostatin (MSTN) is a member of the transforming growth factor-β superfamily of cytokines
and is a negative regulator of skeletal muscle mass. Compared with MSTN+/+ mice, the …

Aim: Myostatin has been characterized as a negative regulator of skeletal muscle growth. To
examine a probable function of myostatin during the adaptation of skeletal muscle in …