Microphthalmia transcription factor expression in cutaneous benign, malignant melanocytic, and nonmelanocytic tumors
R King, PB Googe, KN Weilbaecher… - The American journal …, 2001 - journals.lww.com
The protein encoded by the microphthalmia (mi) gene is a transcription factor essential for
the development and survival of melanocytes. Using a monoclonal antibody generated …
the development and survival of melanocytes. Using a monoclonal antibody generated …
Microphthalmia transcription factor: a sensitive and specific melanocyte marker for melanoma diagnosis
R King, KN Weilbaecher, G McGill, E Cooley… - The American journal of …, 1999 - Elsevier
Malignant melanomas do not uniformly retain expression of melanocytic gene products—an
observation associated with diagnostic dilemmas. Microphthalmia transcription factor (Mitf) …
observation associated with diagnostic dilemmas. Microphthalmia transcription factor (Mitf) …
Role for microphthalmia transcription factor in the diagnosis of metastatic malignant melanoma
SR Granter, KN Weilbaecher, C Quigley… - Applied …, 2002 - journals.lww.com
Microphthalmia transcription factor (Mitf), a protein critical for the embryonic development
and postnatal viability of melanocytes, is a master lineage regulator and modulates …
and postnatal viability of melanocytes, is a master lineage regulator and modulates …
Microphthalmia transcription factor: not a sensitive or specific marker for the diagnosis of desmoplastic melanoma and spindle cell (non-desmoplastic) melanoma
SR Granter, KN Weilbaecher, C Quigley… - The American journal …, 2001 - journals.lww.com
Microphthalmia transcription factor (Mitf), a melanocytic nuclear protein critical for the
embryonic development and postnatal viability of melanocytes, is a master lineage regulator …
embryonic development and postnatal viability of melanocytes, is a master lineage regulator …
Microphthalmia transcription factor and melanoma cell adhesion molecule expression distinguish desmoplastic/spindle cell melanoma from morphologic mimics
MB Koch, IM Shih, SW Weiss… - The American journal of …, 2001 - journals.lww.com
Desmoplastic/spindle cell melanoma is a rare variant of melanoma. A number of factors
complicate the diagnosis of desmoplastic/spindle cell melanoma, including the variable …
complicate the diagnosis of desmoplastic/spindle cell melanoma, including the variable …
Diagnostic utility of microphthalmia transcription factor in malignant melanoma and other tumors
KL Chang, AL Folpe - Advances in anatomic pathology, 2001 - journals.lww.com
The diagnosis of malignant melanoma is sometimes challenging. Immunohistochemistry for
specific markers of melanocytic differentiation such as HMB-45 and Melan-A can be very …
specific markers of melanocytic differentiation such as HMB-45 and Melan-A can be very …
Microphthalmia transcription factor: a sensitive and specific marker for malignant melanoma in cytologic specimens
CC Dorvault, KN Weilbaecher, H Yee… - … Journal of the …, 2001 - Wiley Online Library
BACKGROUND The diagnosis of melanoma can be difficult because of shared
cytomorphology with other malignant neoplasms. The most commonly used melanocytic …
cytomorphology with other malignant neoplasms. The most commonly used melanocytic …
The melanocyte-specific isoform of the microphthalmia transcription factor affects the phenotype of human melanoma
E Selzer, V Wacheck, T Lucas, E Heere-Ress, M Wu… - Cancer research, 2002 - AACR
The microphthalmia transcription factor MITF plays a pivotal role in the development and
differentiation of melanocytes. The purpose of this work was to investigate the expression …
differentiation of melanocytes. The purpose of this work was to investigate the expression …
Analysis of microphthalmia transcription factor expression in normal tissues and tumors, and comparison of its expression with S-100 protein, gp100, and tyrosinase in …
KJ Busam, K Iversen, KC Coplan… - The American journal of …, 2001 - journals.lww.com
Microphthalmia transcription factor (Mitf) is a nuclear protein involved in the development of
melanocytes and the regulation of melanin synthesis. Recent studies have suggested that …
melanocytes and the regulation of melanin synthesis. Recent studies have suggested that …
Frequent mutations in the MITF pathway in melanoma
JC Cronin, J Wunderlich, SK Loftus… - Pigment cell & …, 2009 - Wiley Online Library
Microphthalmia‐associated transcription factor (MITF) is involved in melanocyte cell
development, pigmentation and neoplasia. To determine whether MITF is somatically …
development, pigmentation and neoplasia. To determine whether MITF is somatically …
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