Pluripotent stem cells such as embryonic stem cells (ESCs) and induced pluripotent stem
cells (iPSCs) provide great potential as cell sources for gene editing to generate genetically …

This review deals with the latest advances in the study of embryonic stem cells (ESC) and
induced pluripotent stem cells (iPSC) from domesticated species, with a focus on pigs, cattle …

Since the successful isolation, characterization and long-term culture of embryonic stem
cells (ESCs) from mice in the early 1980s and from humans a decade later, considerable …

Establishment of embryonic stem cell (ESC) lines has been successful in mouse and
human, but not in farm animals. Development of direct reprogramming technology offers an …

The development of the induced pluripotent stem cells (iPSC s) technology has
revolutionized the world on the establishment of pluripotent stem cells (PSC s) across a …

Background Induced pluripotent stem cells (iPSCs) have enormous potential in
developmental biology studies and in cellular therapies. Although extensively studied and …

Up until the mid 2000s, the capacity to generate every cell of an organism was exclusive to
embryonic stem cells. In 2006, researchers Takahashi and Yamanaka developed an …

The unlimited proliferative ability and capacity to contribute to germline chimeras make
pluripotent embryonic stem cells (ESCs) perfect candidates for complex genetic …

The recent progress in derivation of pluripotent stem cells (PSCs) from farm animals opens
new approaches not only for reproduction, genetic engineering, treatment and conservation …

Pluripotent stem cells have the capacity to divide indefinitely and to differentiate into all
somatic cells and tissue lines. They can be genetically manipulated in vitro by knocking …