Complement activation and prognosis in patients with type 2 diabetes and myocardial infarction: a report from the DIGAMI 2 trial

LG Mellbin, M Bjerre, S Thiel, TK Hansen - Diabetes Care, 2012 - Am Diabetes Assoc
OBJECTIVE The activation of the complement system may be involved in the pathology of
myocardial infarction (MI) and type 2 diabetes. To explore their potential as prognostic …

Complement activation in acute myocardial infarction: An early marker of inflammation and tissue injury?

L Bavia, KCF Lidani, FA Andrade, MIAH Sobrinho… - Immunology …, 2018 - Elsevier
Background Acute myocardial infarction (AMI) is a potentially fatal condition, being a major
cause of death worldwide. Ischemia suffered during AMI causes tissue damage, leading to …

Complement factor 3 is associated with insulin resistance and with incident type 2 diabetes over a 7-year follow-up period: the CODAM Study

N Wlazlo, MMJ Van Greevenbroek, I Ferreira… - Diabetes …, 2014 - Am Diabetes Assoc
OBJECTIVE Immune dysregulation can affect insulin resistance (IR) and β-cell function and
hence contribute to development of type 2 diabetes mellitus (T2DM). The complement …

Association of complement C3 with incident type 2 diabetes and the mediating role of BMI: a 10-year follow-up study

J Jiang, H Wang, K Liu, S He, Z Li… - The Journal of …, 2023 - academic.oup.com
Context Impairment of immune and inflammatory homeostasis is reported to be one of the
causal factors of diabetes. However, the association of complement C3 levels with incident …

Complement C3 Is a Risk Factor for the Development of Diabetes: A Population-Based Cohort Study

G Engstrom, B Hedblad, KF Eriksson, L Janzon… - Diabetes, 2005 - Am Diabetes Assoc
Cross-sectional studies have reported strong correlations between plasma levels of
complement C3, insulin, and glucose. This prospective study explored whether elevated …

Level of complement activity predicts cardiac dysfunction after acute myocardial infarction treated with primary percutaneous coronary intervention.

S Haahr-Pedersen, M Bjerre, A Flyvbjerg… - The Journal of …, 2009 - europepmc.org
Background The positive effect of reperfusion after ST-elevation myocardial infarction
(STEMI) can be reduced by ischemic/reperfusion (I/R) injury. Mannose-binding-lectin (MBL) …

Plasma C3d levels and ischemic heart disease in type II diabetes

A Figueredo, JL Ibarra, J Bagazgoitia… - Diabetes …, 1993 - Am Diabetes Assoc
OBJECTIVE To test the hypothesis that the complement system may be activated in patients
with type II diabetes and CAD. RESEARCH DESIGN AND METHODS The plasma C3d …

Increased serum concentrations of adhesion molecules but not of chemokines in patients with Type 2 diabetes compared with patients with Type 1 diabetes and latent …

MN Pham, MI Hawa, M Roden… - Diabetic …, 2012 - Wiley Online Library
Diabet. Med. 29, 470–478 (2012) Abstract Aims Systemic concentrations of adhesion
molecules and chemokines are associated with increased risk of cardiovascular …

Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock

HL Orrem, PH Nilsson, SE Pischke… - ESC heart …, 2018 - Wiley Online Library
Aims Heart failure (HF) is an impending complication to myocardial infarction. We
hypothesized that the degree of complement activation reflects severity of HF following acute …

Elevated serum complement C3 levels are related to the development of prediabetes in an adult population: the Tianjin Chronic Low‐Grade Systematic Inflammation …

X Bao, Y Xia, Q Zhang, HM Wu, HM Du, L Liu… - Diabetic …, 2016 - Wiley Online Library
Aims To investigate whether serum complement C3 is related to the prevalence and
incidence of prediabetes in an adult population. Methods A cross‐sectional (n= 10 206) and …