[PDF][PDF] Relationship between multidrug resistance 1 polymorphisms and the risk of prostate cancer in Chinese populations
FR Shen, CY Yan, M Liu, YH Feng… - Genetics and Molecular …, 2013 - funpecrp.com.br
Prostate cancer is one of the most common malignancies in men. The multidrug resistance 1
gene (MDR1) is an important candidate gene for prostate cancer. The aim of this study was …
gene (MDR1) is an important candidate gene for prostate cancer. The aim of this study was …
Polymorphisms in CYP1A1 gene are associated with male infertility in a Chinese population
N Lu, B Wu, Y Xia, W Wang, A Gu… - … journal of andrology, 2008 - Wiley Online Library
Summary Cytochrome P4501A1 (CYP1A1) is a key enzyme in phase I bioactivation of
polycyclic aromatic hydrocarbons (PAHs), which have potential reproductive toxicity. The …
polycyclic aromatic hydrocarbons (PAHs), which have potential reproductive toxicity. The …
[HTML][HTML] Association of CYP1A1 and glutathione S-transferase polymorphisms with male factor infertility
SE Aydos, M Taspinar, A Sunguroglu, K Aydos - Fertility and sterility, 2009 - Elsevier
OBJECTIVE: To examine whether a relationship exists between genetic polymorphisms of
glutathione S-transferase (GST) M1 and T1, CYP1A1∗ 2C, and male factor infertility …
glutathione S-transferase (GST) M1 and T1, CYP1A1∗ 2C, and male factor infertility …
[HTML][HTML] Association of CYP1A1* 2A polymorphism with idiopathic non-obstructive azoospermia in a south indian cohort
SS Ramgir, N Sekar, D Jindam… - International Journal of …, 2017 - ncbi.nlm.nih.gov
Background: Infertility is the inability of a couple to conceive after one and a half years of
unprotected sex. Male infertility, which accounts for almost half of infertility cases, is …
unprotected sex. Male infertility, which accounts for almost half of infertility cases, is …
[HTML][HTML] The association between polymorphisms in the MDR1 gene and risk of cancer: a systematic review and pooled analysis of 52 case–control studies
LH Wang, YB Song, WL Zheng, L Jiang, WL Ma - Cancer cell international, 2013 - Springer
Background The multidrug resistance (MDR) 1 gene encodes a 170-kDa membrane
transporter called P-glycoprotein, which plays an important role in protecting cells against …
transporter called P-glycoprotein, which plays an important role in protecting cells against …
The single nucleotide polymorphism and haplotype analysis of MDR1 in Jiangsu Han population of China
H Qiu, H Dong, S Pan, K Miao - Biomedicine & Pharmacotherapy, 2012 - Elsevier
The aim of this study was to perform the frequency distribution of MDR1 gene SNPs and
haplotypes of Jiangsu Han population in China. A total of 225 Jiangsu Han unrelated …
haplotypes of Jiangsu Han population in China. A total of 225 Jiangsu Han unrelated …
Distribution of the single nucleotide polymorphism C3435T of MDR1 gene among people in Western Australia, Australia
What is known: Ethnic variation as well as the population frequency of the MDR1 C3435T
transition has been observed in the few other populations but not in Australians. Objective …
transition has been observed in the few other populations but not in Australians. Objective …
[HTML][HTML] Correlation of single nucleotide polymorphisms of PRM1, PRM2, PYGO2, and DAZL genes with male infertility in north west of Iran
E Ghadirkhomi, SA Angaji, B Beikzadeh… - Turkish Journal of …, 2022 - ncbi.nlm.nih.gov
Objective: Almost half of infertility is related to male factors. Although the effect of genetic
factors on male infertility is identified, about 30%-50% still has no proven cause and is …
factors on male infertility is identified, about 30%-50% still has no proven cause and is …
Increased frequencies of cytochrome P4501A1 polymorphisms in infertile men
E Fritsche, HC Schuppe, O Döhr, T Ruzicka… - Andrologia, 1998 - Wiley Online Library
Genetic factors that could mediate the pathogenesis of male reproductive disorders are
largely unclear. Polymorphisms of cytochrome P4501A1 (CYP1A1), a key enzyme in the …
largely unclear. Polymorphisms of cytochrome P4501A1 (CYP1A1), a key enzyme in the …
Genetic variability and haplotype profile of MDR1 in Saudi Arabian males
AM Al-Mohizea, KM Alkharfy, KM Bagulb… - Molecular biology …, 2012 - Springer
Polymorphisms in multidrug resistance (MDR1) gene play an important role in influencing
the pharmacological action and toxicity profile of a large number of therapeutic agents, and …
the pharmacological action and toxicity profile of a large number of therapeutic agents, and …