Association of CYP1A1 gene polymorphism with recurrent pregnancy loss in the South Indian population

V Suryanarayana, M Deenadayal… - Human …, 2004 - academic.oup.com
BACKGROUND: We investigated the relationship between idiopathic recurrent pregnancy
loss (RPL) and genetic polymorphisms in phase I and phase II detoxification genes which …

Human MDR1 polymorphism: G2677T/A and C3435T have no effect on MDR1 transport activities

N Morita, T Yasumori, K Nakayama - Biochemical pharmacology, 2003 - Elsevier
The two most frequently observed single nucleotide polymorphisms (SNPs) of the human
multidrug resistance 1 (MDR1) gene are 2677G/T/A (893Ala/Ser/Thr) and 3435C/T (no …

Cytochrome P450‐2D6* 4 polymorphism seminal relationship in infertile men

A Zalata, AZ El‐Samanoudy, G Osman, S Elhanbly… - Andrologia, 2015 - Wiley Online Library
This study aimed to assess cytochrome (CY) P450‐2D6* 4 polymorphism relationship with
semen variables in infertile men. In all, 308 men were included; fertile normozoospermia …

Role of glutathione S‐transferase Mu‐1 (GSTM1) polymorphism in oligospermic infertile males

G Tirumala Vani, N Mukesh, B Siva Prasad… - Andrologia, 2010 - Wiley Online Library
The aim of this study was to examine whether an association exists between glutathione S‐
transferase Mu‐1 (GSTM1) gene polymorphism and idiopathic male infertility. Forty‐two men …

[HTML][HTML] Glutathione peroxidase 3 (extracellular isoform) levels and functional polymorphisms in fertile and infertile men

M Pournasir, S Ghorbian, T Ghasemnejad… - Middle East Fertility …, 2021 - Springer
Background Oxidative stress has an undeniable role in the impairment of sperm function
and idiopathic male infertility. On the other hand, the local antioxidant system particularly …

The association of GSTP1 polymorphisms with male idiopathic infertility

NA Kurashova, EV Belyaeva, OA Ershova… - …, 2019 - journals.eco-vector.com
Аннотация Цель исследования: установить ассоциацию двух полиморфных локусов
Ile105Val, Ala114Val гена GSTP1 (глутатионтрансфераза класса пи-1) с бесплодием у …

[HTML][HTML] Multidrug resistance gene 1 C1236T polymorphism and susceptibility to leukemia: A meta-analysis

L Ma, H Liu, L Ruan, X Yang… - Biomedical …, 2015 - spandidos-publications.com
Several studies have investigated the association between multidrug resistance gene
(MDR1) C1236T polymorphism and leukemia risk, however, these published studies have …

MDR1 gene polymorphisms and acute myeloid leukemia AML susceptibility in A Moroccan adult population: A case-control study and meta-analysis

ABO Kaltoum, N Sellama, D Hind, K Yaya… - Current research in …, 2020 - Elsevier
Introduction The multidrug resistance 1 (MDR1) gene plays an important function in
carcinogens detoxification and drugs metabolism. Many authors reported that MDR1 gene …

Variable expression of P-glycoprotein in the human placenta and its association with mutations of the multidrug resistance 1 gene (MDR1, ABCB1)

M Hitzl, E Schaeffeler, B Hocher… - Pharmacogenetics …, 2004 - journals.lww.com
The MDR1 gene product P-glycoprotein in the human placenta is important for protecting the
fetus from unintended, harmful drug exposure, but also for limiting the access of therapeutic …

Genetic polymorphisms in MDR1 and CYP3A5 and MDR1 haplotype in mainland Chinese Han, Uygur and Kazakh ethnic groups

D Li, GL Zhang, YQ Lou, Q Li, X Wang… - Journal of clinical …, 2007 - Wiley Online Library
Background and objective: The drug transporter MDR1 and the drug metabolizing enzyme
CYP3A are the two major biological factors determining the pharmacokinetics of many …