Hepatocellular carcinoma (HCC) is the third most deadly cancer in the world. New treatment
strategies are desperately needed due to limited standard therapies. Activation of the Erk …

Malignant melanoma is the most deadly form of skin cancer due to its highly metastatic
nature. Untargeted therapies are ineffective for treating metastatic disease, leading to the …

The most common disease states of chronic liver illnesses include alcoholic liver disease
(ALD), and viral hepatitis can progress to hepatocellular carcinoma (HCC). However, the …

Background and Aim. Selenium possesses anticancer and antiviral properties, but its
mechanism of action remains unclear. Especially, the impact of selenium on hepatitis B virus …

The need to explore new alternative therapeutic strategies and chemoprevention methods
for hepatocellular carcinoma is growing significantly. Selenium is a trace element that plays …

Selenium has good antitumor effects in vitro, but the hypoxic microenvironment in solid
tumors makes its clinical efficacy unsatisfactory. We hypothesized that the combination with …

Hepatocellular carcinoma (HCC) accounts for most of primary liver cancer, of which five-year
survival rate remains low and chemoprevention has become a strategy to reduce disease …

Selenium has been shown to sustain the growth of selected human hepatocellular
carcinoma cell lines under serum-free conditions, but the detailed mechanism remained …

Selenium is a micronutrient that had been suggested to reduce the risk of cancer.
Hepatocellular carcinoma (HCC), a prevalent disease and one of the most lethal cancers in …

Selenium has received much attention as an anticancer agent, although the mechanisms of
action underlying its pro-apoptotic properties remain unclear. Tumors that respond well to …