A series of novel resveratrol derivatives were designed, synthesised and evaluated as
potential therapeutic agents for the treatment of Alzheimer's disease. Among these …

A series of multitarget-directed resveratrol derivatives was designed and synthesized for the
treatment of Alzheimer's disease (AD). In vitro studies indicated that most of the target …

A series of imine resveratrol derivatives (1–20) have been designed, synthesized, and
evaluated as multi-targeted compounds for the treatment of Alzheimer's disease (AD). In …

Amyloid-β aggregation inhibitors are expected to be therapeutic or prophylactic agents for
Alzheimer's disease. Rosmarinic acid, which is one of the main aggregation inhibitors …

Abstract The 3-hydroxypyran-4-one moiety (maltol) was incorporated into the structure of
resveratrol to achieve a series of resveratrol-maltol hybrids (8a–8k) as novel multi-target …

A series of deferiprone-resveratrol hybrids have been designed and synthesized as
multitarget-directed ligands (MTDLs) through merging the chelating moiety 3-hydroxypyridin …

A series of novel multipotent 2-piperidone derivatives were designed, synthesized and
biologically evaluated as chemical agents for the treatment of Alzheimer's disease (AD). The …

A series of prenylated resveratrol derivatives were designed, semisynthesized and
biologically evaluated for inhibition of β-secretase (BACE1) and amyloid-β (Aβ) aggregation …

A series of resveratrol dimer derivatives against Alzheimer's disease (AD) was obtained by
structural modification and transformation using resveratrol as substrate. Biological analysis …

Considering the complex pathogenesis factors of Alzheimer's disease (AD), the multitarget-
directed ligand strategy is expected to provide superior effects to fight AD, instead of the …