An organism's ability to mount a physiological response to external stressors is fundamental
to its interaction with the environment. Experimental exploration of these interactions …

Animal response to changes in environmental cues is a complex dynamical process that
occurs at diverse molecular and cellular levels. To gain a quantitative understanding of such …

The nematode Caenorhabditis elegans is an important model organism in genetic research
and drug screening because of its relative simplicity, ease of maintenance, amenability to …

Caenorhabditis elegans are widely used to study aging biology. The standard practice in C.
elegans aging studies is to culture groups of worms on solid nematode growth media …

The nematode C. elegans is an excellent model organism for studying behavior at the
neuronal level. Because of the organism's small size, it is challenging to deliver stimuli to C …

In a typical high-throughput drug screening (HTS) process, up to millions of chemical
compounds are applied to cells cultured in well plates, aiming to find molecules that exhibit …

Organisms are often exposed to fluctuating environments and changes in intracellular
homeostasis, which can have detrimental effects on their proteome and physiology. Thus …

With its small size, short lifespan, and easy genetics, Caenorhabditis elegans offers a
convenient platform to study the impact of microbial isolates on host physiology. It also …

The nematode Caenorhabditis elegans is a suitable model organism in drug screening.
Traditionally worms are grown on agar plates, posing many challenges for long-term culture …

Due to the development of resistance to anthelmintics there is a continuous requirement to
search for new anthelmintics that act at novel sites. Until now, new anthelmintics have been …