Study of SR 142801, a new potent non‐peptide NK3 receptor antagonist on cardiovascular responses in conscious guinea‐pig
A Roccon, D Marchionni… - British journal of …, 1996 - Wiley Online Library
1 The cardiovascular responses to intravenous (iv) injection of natural tachykinins,
substance P (SP), neurokinin A (NKA), neurokinin B (NKB) and selective tachykinin (NK) …
substance P (SP), neurokinin A (NKA), neurokinin B (NKB) and selective tachykinin (NK) …
Effects of the tachykinin NK1 receptor antagonist, RP 67580, on central cardiovascular and behavioural effects of substance P, neurokinin A and neurokinin B
J Culman, B Wiegand, H Spitznagel… - British journal of …, 1995 - Wiley Online Library
1 We have investigated the effects of the non‐peptide NK1 tachykinin receptor antagonist,
RP 67580, and its inactive enantiomer, RP 68651, on the cardiovascular and behavioural …
RP 67580, and its inactive enantiomer, RP 68651, on the cardiovascular and behavioural …
Cardiovascular and behavioural effects of intracerebroventricularly administered tachykinin NK3 receptor antagonists in the conscious rat
E Cellier, L Barbot, D Regoli… - British journal of …, 1997 - Wiley Online Library
1 In the conscious rat, three tachykinin NK3 receptor antagonists, namely SR142801 ((S)‐
(N)‐(1‐(3‐(1‐benzoyl‐3‐(3, 4‐dichlorophenyl) piperidin‐3‐yl) propyl)‐4‐phenylpiperidin‐4 …
(N)‐(1‐(3‐(1‐benzoyl‐3‐(3, 4‐dichlorophenyl) piperidin‐3‐yl) propyl)‐4‐phenylpiperidin‐4 …
Cardiovascular and behavioural effects of centrally administered tachykinins in the rat: characterization of receptors with selective antagonists
P Picard, D Regoli, R Couture - British journal of pharmacology, 1994 - Wiley Online Library
1 The effects of intracerebroventricular (icv) injection of selective and potent NK1 (RP
67580), NK2 (SR 48968) and NK3 (R 486,[Trp7, β‐Ala8] NKA (4–10)) receptor antagonists …
67580), NK2 (SR 48968) and NK3 (R 486,[Trp7, β‐Ala8] NKA (4–10)) receptor antagonists …
Peripheral effects of three novel non-peptide tachykinin NK1 receptor antagonists in the anaesthetized rat
E Cellier, C Fayolle, PA Hipskind, S Iyengar… - European journal of …, 1996 - Elsevier
Three novel non-peptide tachykinin NK1 receptor antagonists were assessed on the
transient fall in mean arterial blood pressure and the salivation induced by iv substance P …
transient fall in mean arterial blood pressure and the salivation induced by iv substance P …
Inhibition of tachykinin-induced hypotension in dogs by CP-96,345, a selective blocker of NK-1 receptors
JW Constantine, WS Lebel, HA Woody - Naunyn-Schmiedeberg's archives …, 1991 - Springer
The effects of substance P, neurokinin A, neurokinin B,[Sar 9, Met (O 2) 11]-substance P,[Nle
10] neurokinin A (4–10) and senktide {succinyl-[Asp 6, McPhe 8]-substance P (6–11)} on …
10] neurokinin A (4–10) and senktide {succinyl-[Asp 6, McPhe 8]-substance P (6–11)} on …
Cardiovascular and behavioural effects of centrally administered neuropeptide K in the rat: receptor characterization
A Prat, P Picard, R Couture - British journal of pharmacology, 1994 - Wiley Online Library
1 The cardiovascular and behavioural responses to intracerebroventricularly (icv)
administered neuropeptide K (NPK) were studied in conscious rats. The central effects of …
administered neuropeptide K (NPK) were studied in conscious rats. The central effects of …
In vitro and in vivo biological activities of SR140333, a novel potent non-peptide tachykinin NK1 receptor antagonist
X Emonds-Alt, JD Doutremepuich, M Heaulme… - European journal of …, 1993 - Elsevier
Abstract (S) 1-{; 2-[3-(3, 4-dichlorophenyl)-1-(3-isopropoxyphenylacetyl) piperidin-3-yl]
ethyl};-4-phenyl-1-azoniabicyclo [2.2. 2] octane chloride (SR140333) is a new non-peptide …
ethyl};-4-phenyl-1-azoniabicyclo [2.2. 2] octane chloride (SR140333) is a new non-peptide …
Cardiovascular effects of CP-96,345, a non-peptide blocker of tachykinin NK1 receptors
JW Constantine, WS Lebel, HA Woody… - European journal of …, 1994 - Elsevier
Abstract CP-96,345, a non-peptide, selective tachykinin NK 1 receptor blocker and its
inactive enantiomer, CP-96,344, inhibit ligand binding of phenylalkylamine but not …
inactive enantiomer, CP-96,344, inhibit ligand binding of phenylalkylamine but not …
Characterization of the peripheral action of neurokinins and neurokinin receptor selective agonists on the rat cardiovascular system
R Couture, O Laneuville, C Guimond… - Naunyn-Schmiedeberg's …, 1989 - Springer
The effects on mean arterial pressure (MAP) and heart rate (HR) of increasing doses (0.65–
65 nmol/kg) of substance P (SP), neurokinin A (NKA), neurokinin B (NKB) and selective …
65 nmol/kg) of substance P (SP), neurokinin A (NKA), neurokinin B (NKB) and selective …