Acetaminophen (APAP) is the most popular mild analgesic and antipyretic drug used
worldwide. APAP overdose leads to drug-induced hepatotoxicity and can cause hepatic …

Acetaminophen (APAP), the most commonly sold over-the-counter antipyretic analgesic, is
generally considered harmless at therapeutic doses. However, APAP overdose causes …

Abstract Acetaminophen (paracetamol, N-acetyl-p-aminophenol; APAP) is the most popular
analgesic/antipyretic agent in the world. APAP has been regarded as a safer drug compared …

Acetaminophen (APAP) overdose is the leading cause of drug-induced acute liver failure in
many developed countries. Mitochondrial oxidative stress is considered to be the …

Hepatic injury and subsequent hepatic failure due to both intentional and non-intentional
overdose of acetaminophen (APAP) has affected patients for decades, and involves the …

Acetaminophen (APAP) is one of the most popular and safe pain medications worldwide.
However, due to its wide availability, it is frequently implicated in intentional or unintentional …

Acetaminophen (APAP), a widely used antipyretic and analgesic drug in clinics, is relatively
safe at therapeutic doses; however, APAP overdose may lead to fatal acute liver injury …

Significance: Acetaminophen (APAP) is one of the quantitively most consumed drugs
worldwide. Although safe at therapeutic doses, intentional or unintentional overdosing …

Acetaminophen (APAP) overdose is the most common cause of acute liver failure in the US,
and decades of intense study of its pathogenesis resulted in the development of the antidote …

Liver injury and acute liver failure caused by acetaminophen (APAP, N-acetyl-p-
aminophenol, paracetamol) overdose is a significant clinical problem in most western …