Structure-affinity studies of C-terminally modified analogs of neuropeptide Y led to a novel class of peptidic Y1 receptor antagonist

S Hoffmann, B Rist, G Videnov, G Jung… - Regulatory peptides, 1996 - Elsevier
A novel type of C-terminally modified analogs of the 36-mer peptide hormone neuropeptide
Y has been synthesized, characterized and tested with respect to receptor affinity and …

Brain peptide YY receptors: highly conserved characteristics throughout vertebrate evolution

M OKITA, A INUI, Y HIROSUE, M MIURA… - …, 1991 - academic.oup.com
We have shown previously that peptide YY (PYY) receptors are uniquely distributed in
various mammalian brains and also have identified the receptor from porcine hippocampal …

Design and discovery of neuropeptide Y1 receptor antagonists

J Wright - Drug discovery today, 1997 - Elsevier
Neuropeptide Y (NPY) has been the focus of much attention since its discovery as the most
abundant peptide in mammalian brain. It has been implicated in many roles in both the …

Binding properties of three neuropeptide Y receptor subtypes from zebrafish: comparison with mammalian Y1 receptors

MM Berglund, I Lundell, C Cabrele… - Biochemical …, 2000 - Elsevier
Neuropeptide Y (NPY) and peptide YY (PYY) are two related 36-amino-acid peptides found
in all vertebrates and are involved in many physiological processes. Five receptor subtypes …

Extraordinary structural diversity of NPY-family receptors

D Larhammar - Neuropeptide Y and drug development, 1997 - Elsevier
Publisher Summary This chapter discusses extraordinary structural diversity of neuropeptide
Y (NPY)-family receptors. The molecular cloning of receptors, which bind to neuropeptide Y …

Neuropeptide Y: At the dawn of subtype selective antagonists

PA Hipskind, DR Gehlert - Annual reports in medicinal chemistry, 1996 - Elsevier
Publisher Summary This chapter discusses the essential elements of neuropeptide Y (NPY)
pharmacology, receptor distribution, and molecular biology as well as the recent …

[引用][C] Characterization of Receptor Types for Neuropeptide Y and Related Peptides

C Wahlestedt - Protocols for Neural Cell Culture, 1992 - Totowa, NJ: Humana Press

[HTML][HTML] Purification and Biochemical Characterization of Neuropeptide Y2 Receptor (∗)

SJ Wimalawansa - Journal of Biological Chemistry, 1995 - ASBMB
Neuropeptide Y (NPY) receptors consist of three subtypes, designated NPY 1, NPY 2, and
NPY 3. The Y 1 receptor has been cloned. The present study reports the purification of the …

[引用][C] Sponsor. Dates: Place: Theme

J Koenig - 1990 - Springer
The isolation and characterization of Neuropeptide Y (NPY) in the early 1980's has
stimulated a number of studies into the molecular biology, biochemistry and physiology of …

Cloning and characterization of the guinea pig neuropeptide Y receptor Y5

I Lundell, H Eriksson, U Marklund, D Larhammar - Peptides, 2001 - Elsevier
The Y5 receptor has been postulated to be the main receptor mediating NPY-induced food
intake in rats, based on its pharmacological profile and mRNA distribution. To further …