Excessive recombination between repeated, interspersed, and diverged DNA sequences is
a potential source of genomic instability. We have investigated the possibility that a …

The idea that there might be a process capable of recognizing and repairing incorrect base
pairs in double-stranded DNA (mismatch repair) was originally proposed to account for …

Previous studies have shown that inactivation of the MutS or MutL mismatch repair enzymes
increases the efficiency of homeologous recombination between Escherichia coli and …

To get more insight into the control of homologous recombination between diverged DNA by
the Mut proteins of the long-patch mismatch repair system, we have studied interspecies …

We have used artificially constructed heteroallelic heteroduplex molecules of bacteriophage
lambda DNA to transfect Escherichia coli, and E. coli mutants deficient in various functions …

A genetic analysis of interspecies recombination in Escherichia coli between the linear Hfr
DNA from Salmonella typhimurium and the circular recipient chromosome reveals some …

A mismatch can be defined as any noncomplementary base pair in double stranded DNA.
Mismatched base pairs (or unpaired bases) can occur in vivo as a result of:(a) errors in DNA …

The mismatch repair system is involved in the maintenance of genomic integrity by editing
DNA replication and recombination. However, although most mutations are neutral or …

The ability of related DNAs to undergo recombination decreases with increased sequence
divergence. Mismatch repair has been proposed to be a key factor in preventing …

The process of mismatch repair was first postulated to explain the results of experiments on
genetic recombination and bacterial mutagenesis. Mismatch repair has long been known to …