Plasmid heteroduplexes were constructed that contain 1, 2, 3, 4, or 5 unpaired bases within
the mnt gene. These were used to assess the efficiency of repair of small heterologous …

Previous biochemical analysis ofEscherichia coli methyl-directed mismatch repair implicates
three redundant single-strand DNA-specific exonucleases (RecJ, ExoI, and ExoVII) and at …

DNA-mismatch correction, the recognition and processing of base-pairing errors within the
Watson-Crick helix, has been demonstrated in bacteria, fungi and higher eukaryotes. It is …

UvrD (DNA helicase II) is an essential component of two major DNA repair pathways in
Escherichia coli: methyl‐directed mismatch repair and UvrABC‐mediated nucleotide …

An assay has been developed that permits analysis of DNA mismatch repair in cell-free
extracts of Escherichia coli. The method relies on repair of heteroduplex molecules of f1 …

In most organisms, the mismatch repair (MMR) system plays an important role in
substantially lowering mutation rates and blocking recombination between nonidentical …

The mutD (dnaQ) gene of Escherichia coli codes for the proofreading activity of DNA
polymerase III. The very strong mutator phenotype of mutD5 strains seems to indicate that …

Nonidentical recombination substrates recombine less efficiently than do identical
substrates in yeast, and much of this inhibition can be attributed to action of the mismatch …

Multicopy single‐stranded DNA (msDNA) molecules consist of single‐stranded DNA
covalently linked to RNA. In Escherichia coli, such molecules are encoded by genetic …

Circular heteroduplex DNAs of bacteriophage phi X174 have been constructed carrying
either a G: T (Eam+/Eam3) or a G: A (Bam+/Bam16) mismatch and containing either two …