Comorbidities, treatment, and pathophysiology in restless legs syndrome

C Trenkwalder, R Allen, B Högl, S Clemens… - The Lancet …, 2018 - thelancet.com
Restless legs syndrome, also known as Willis-Ekbom disease, is a common neurological
condition whose manifestation is affected by complex environmental and genetic …

New concepts in the management of restless legs syndrome

D Garcia-Borreguero, I Cano-Pumarega - bmj, 2017 - bmj.com
Restless legs syndrome (RLS), also known as Willis-Ekbom disease (WED) is a
neurological condition with an overall prevalence in adults of 5-10% in Europe and North …

[HTML][HTML] Restless legs syndrome

L Klingelhoefer, K Bhattacharya, H Reichmann - Clinical Medicine, 2016 - Elsevier
Restless legs syndrome (RLS), also known as Willis-Ekbom disease (WED), is a common
movement disorder characterised by an uncontrollable urge to move because of …

The restless legs syndrome

C Trenkwalder, W Paulus, AS Walters - The lancet neurology, 2005 - thelancet.com
The restless legs syndrome is a common disorder that encompasses an idiopathic form of
genetic or unknown origin and symptomatic forms associated with many causes …

Willis-Ekbom Disease Foundation revised consensus statement on the management of restless legs syndrome

MH Silber, PM Becker, C Earley… - Mayo Clinic …, 2013 - Elsevier
Restless legs syndrome (RLS)/Willis-Ekbom disease (WED) is a common disorder,
occurring at least twice a week and causing at least moderate distress in 1.5% to 2.7% of the …

An update on restless legs syndrome (Willis-Ekbom disease): clinical features, pathogenesis and treatment

D Garcia-Borreguero, AM Williams - Current opinion in neurology, 2014 - journals.lww.com
Recent epidemiological findings have shown that RLS/WED is a common neurological
disorder that affects up to 5% of the adult population in Western countries. In moderate and …

A randomized, double-blind placebo-controlled trial of iron in restless legs syndrome

BJ Davis, A Rajput, ML Rajput, EA Aul… - European …, 2000 - karger.com
Background: Previous open-label trials have shown iron to be efficacious in the treatment of
restless legs syndrome. We performed a randomized, double-blind, placebo-controlled trial …

Update on restless legs syndrome: from mechanisms to treatment

P Gonzalez-Latapi, R Malkani - Current neurology and neuroscience …, 2019 - Springer
Abstract Purpose of Review To provide an overview of the molecular pathways and recent
genetic risk loci associated with restless legs syndrome/Willis-Ekbom disease (RLS/WED) …

[HTML][HTML] Guidelines for the first-line treatment of restless legs syndrome/Willis–Ekbom disease, prevention and treatment of dopaminergic augmentation: a combined …

D Garcia-Borreguero, MH Silber, JW Winkelman… - Sleep medicine, 2016 - Elsevier
A Task Force was established by the International Restless Legs Syndrome Study Group
(IRLSSG) in conjunction with the European Restless Legs Syndrome Study Group …

Iron, dopamine, genetics, and hormones in the pathophysiology of restless legs syndrome

FH Khan, CD Ahlberg, CA Chow, DR Shah, BB Koo - Journal of neurology, 2017 - Springer
Restless legs syndrome (RLS) is a common, chronic neurologic condition, which causes a
persistent urge to move the legs in the evening that interferes with sleep. Human and animal …