The Transgenic livestock can be useful for the production of disease-resistant animals, pigs
for xenotranplantation, animal bioreactor for therapeutic recombinant proteins and disease …

The production of transgenic farm animals (eg, cattle) via genome engineering for the gain
or loss of gene functions is an important undertaking. In the initial stages of genome …

New techniques in molecular biology help us for better understanding of biological
processes. As biologists we resort to powerful approaches for efficient gene transfer which …

Classic transgenic technology couldn't play its great role in animal breeding because of
randomly integration and unstable heredity of exogenous genes. A new world has been …

Historically, genetic engineering in livestock proved to be challenging. Without stable
embryonic stem cell lines to utilize, somatic cell nuclear transfer (SCNT) had to be employed …

In the past few years, new technologies have arisen that enable higher efficiency of gene
editing. With the increase ease of using gene editing technologies, it is important to consider …

Pigs are an important resource in agriculture and serve as a model for human diseases. Due
to their physiological and anatomical similarities with humans, pigs can recapitulate …

Genetically modified animals, especially rodents, are widely used in biomedical research.
However, non-rodent models are required for efficient translational medicine and preclinical …

Due to the lack of germline transmitting pluripotent stem cells (PSCs) cell lines and the
extreme difficulty of somatic cell nuclear transfer (SCNT) in rabbit, the gene targeting …

Traditionally, genetic engineering in the pig was a challenging task. Genetic engineering of
somatic cells followed by somatic cell nuclear transfer (SCNT) could produce genetically …