The effects of neurokinins and neurokinin receptor selective agonists have been
investigated on human intralobar pulmonary vessels. Substance P (SP) and [Sar 9 Met (O 2) …

The effects of tachykinin NK1, NK2 and NK3 receptor agonists and antagonists were
measured on blood pressure (MAP) and heart rate (HR) after bilateral microinjection into the …

The pharmacological characterization of the tachykinin receptors involved in spinal and
supraspinal cardiovascular regulation is reviewed in this report. In conscious rats, substance …

Four neurokinin anatagonists of different size have been used to counteract the myotropic
effects of substance P, neurokinin A and neurokinin B in isolated organs containing a single …

Three novel non-peptide tachykinin NK1 receptor antagonists were assessed on the
transient fall in mean arterial blood pressure and the salivation induced by iv substance P …

Selective tachykinin agonists were used to identify cardiac and coronary responses
mediated by specific tachykinin receptor subtypes in isolated, perfused guinea pig hearts …

Abstract cDNA clones for NK-2 receptors (NK-2R) were isolated from guinea-pig lung (GP1)
and rabbit pulmonary artery (Rpa) using a polymerase chain reaction based methodology …

A series of 21 peptides were synthesized and tested in a variety of isolated organs in order
to determine their potential as neurokinin-2 (NK-2) antagonists. The peptides have been …

Goals of this study were to identify and characterize effects of neurokinin A (NKA) in isolated
guinea pig hearts. Bradycardia, augmentation of ventricular contractions, and reduction of …

Several neurokinins, namely substance P, neurokinin A, neurokinin B,[β-Ala 8] neurokinin A-
(4–10) and senktide, were tested on noradrenaline-precontracted rabbit aortic rings to …