Receptor-selective, peptidase-resistant agonists at neurokinin NK-1 and NK-2 receptors: new tools for investigating neurokinin function
RM Hagan, SJ Ireland, CC Jordan, IJM Beresford… - Neuropeptides, 1991 - Elsevier
The pharmacological profiles of two novel neurokinin agonists have been investigated. δAva
[L-Pro 9, N-MeLeu 10] SP (7–11)(GR73632) and [Lys 3, Gly 8-R-γ-lactam-Leu 9] NKA (3 …
[L-Pro 9, N-MeLeu 10] SP (7–11)(GR73632) and [Lys 3, Gly 8-R-γ-lactam-Leu 9] NKA (3 …
Pharmacology of neurokinin receptors
D Regoli, F Nantel - Biopolymers: Original Research on …, 1991 - Wiley Online Library
The neurokinins are a group of naturally occurring peptides with the common C‐terminal
sequence Phe‐X‐Gly‐Leu‐Met· NH2. They include substance P (SP), neurokinin A (NKA) …
sequence Phe‐X‐Gly‐Leu‐Met· NH2. They include substance P (SP), neurokinin A (NKA) …
Bronchoconstrictor and hypotensive effects in relation to pharmacokinetics of tachykinins in the guinea-pig—evidence for extraneuronal cleavage of neuropeptide K to …
CR Marding, E Theodorsson-Norheim… - Naunyn-Schmiedeberg's …, 1987 - Springer
The biological effects of the tachykinins substance P (SP), neurokinin A (NKA) and
neuropeptide K (NPK) were studied in relation to their pharmacokinetic properties in the …
neuropeptide K (NPK) were studied in relation to their pharmacokinetic properties in the …
Neurokinin receptors (NK1,NK2) in the mouse: a pharmacological study
SN Allogho, XK Nguyen-Le, F Gobeil… - Canadian journal of …, 1997 - cdnsciencepub.com
Experiments were performed on strips of mouse stomach and urinary bladder to
characterize the receptors involved in the contractile responses of these tissues to …
characterize the receptors involved in the contractile responses of these tissues to …
In vitro and in vivo pharmacology of S 16474, a novel dual tachykinin NK1 and NK2 receptor antagonist
P Robineau, M Lonchampt, N Kucharczyk… - European journal of …, 1995 - Elsevier
Since tachykinins released from lung sensory nerve endings are thought to play a role in
inflammatory diseases of airways via NK1 and NK2 receptors, dual tachykinin NK1 and NK2 …
inflammatory diseases of airways via NK1 and NK2 receptors, dual tachykinin NK1 and NK2 …
Non-peptide angiotensin receptor antagonists bind to tachykinin NK3 receptors of rat and guinea pig brain
L Chretien, G Guillemette, D Regoli - European journal of pharmacology, 1994 - Elsevier
Abstract [3 H] Senktide, a highly selective tachykinin NK 3 receptor agonist, was used to
study tachykinin NK 3 receptors of rat and guinea pig brain. Guinea pig brain membranes …
study tachykinin NK 3 receptors of rat and guinea pig brain. Guinea pig brain membranes …
In vivo and in vitro pharmacology of SR 48,968, a non-peptide tachykinin NK2 receptor antagonist
CA Maggi, R Patacchini, S Giuliani… - European journal of …, 1993 - Elsevier
Abstract The activity of SR 48,968, a novel non-peptide antagonist of tachykinin NK 2
receptors was evaluated in vitro in several bioassays for the NK 2 receptor (rabbit pulmonary …
receptors was evaluated in vitro in several bioassays for the NK 2 receptor (rabbit pulmonary …
Involvement of NK1 and NK2 Receptors in Pulmonary Responses Elicited by Non-adrenergic, Non-cholinergic Vagal Stimulation in Guinea-pigs
C Savoie, C Tousignant, IW Rodger… - Journal of pharmacy …, 1995 - academic.oup.com
Previous studies from our laboratory using exogenously administered neurokinin (NK)
agonists have shown that both NK1-and NK2-receptor subtypes are involved in plasma …
agonists have shown that both NK1-and NK2-receptor subtypes are involved in plasma …
Tachykinins (substance P, neurokinin A, neuropeptide K, and neurokinin B) in the cerebral circulation: vasomotor responses in vitro and in situ
The vasomotor responses of tachykinins have been studied in the cerebral vasculature of
human, pig, cat, and guinea pig. Substance P (SP), neurokinin A (NKA), neurokinin B (NKB) …
human, pig, cat, and guinea pig. Substance P (SP), neurokinin A (NKA), neurokinin B (NKB) …
[引用][C] Both neurokinin A and substance P bind to NK1 receptors in guinea-pig lung
E Burcher, DJ Watkins, NM O'Flynn - Pulmonary Pharmacology, 1989 - Elsevier
Tachykinins have a number of actions in the respiratory tract. Substance P (SP) is the most
potent tachykinin in stimulation of mucus secretion, while neurokinin A (NKA) is the most …
potent tachykinin in stimulation of mucus secretion, while neurokinin A (NKA) is the most …