Different neurodegenerative disorders often show similar lesions, such as the presence of
amyloid plaques, TAU-neurotangles and synuclein inclusions. The genetically inherited …

Dementia is a complex clinical condition characterized by several cognitive impairments that
interfere with patient independence in executing everyday tasks. Various neurodegenerative …

DNA methylation reactions are regulated, in the first instance, by enzymes and the
intermediates that constitute the 'so called'one-carbon metabolism. This is a complex …

Iraola‐Guzmán S, Estivill X, Rabionet R. DNA methylation in neurodegenerative disorders: a
missing link between genome and environment? The risk of developing neurodegenerative …

DNA methylation has been an important area of research in the study of molecular
mechanism to psychiatric disorders. Recent evidence has suggested that abnormalities in …

Recent studies have suggested a role for epigenetic mechanisms in the complex etiology of
various neurodegenerative diseases. In this review, we discuss advances that have been …

Genome-wide studies related to neurological disorders and neurodegenerative diseases
have pointed to the role of epigenetic changes such as DNA methylation, histone …

A recent expansion of our knowledge about epigenetic changes strongly suggests that
epigenetic rather than genetic features better reflect disease development, and …

Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by the
progressive accumulation of amyloid-beta and neurofibrillary tangles of tau in the neocortex …

Epigenetic alterations represent a sort of functional modifications related to the genome that
are not responsible for changes in the nucleotide sequence. DNA methylation is one of such …