Minimal residual disease after allogeneic stem cell transplant: a comparison among multiparametric flow cytometry, Wilms tumor 1 expression and chimerism status …

G Rossi, AM Carella, MM Minervini, L Savino… - Leukemia & …, 2013 - Taylor & Francis
Relapse represents the main cause of treatment failure after allogeneic stem cell transplant
(allo-SCT). The detection of minimal residual disease (MRD) by multiparametric flow …

[HTML][HTML] Comparison of chimerism and minimal residual disease monitoring for relapse prediction after allogeneic stem cell transplantation for adult acute …

TH Terwey, PG Hemmati, M Nagy, H Pfeifer… - Biology of Blood and …, 2014 - Elsevier
Little data are available on the relative merits of chimerism and minimal residual disease
(MRD) monitoring for relapse prediction after allogeneic hematopoietic stem cell …

Intensive monitoring of minimal residual disease and chimerism after allogeneic hematopoietic stem cell transplantation for acute leukemia in children

T Pincez, R Santiago, H Bittencourt, I Louis… - Bone Marrow …, 2021 - nature.com
Posttransplant leukemia detection before overt relapse is key to the success of
immunotherapeutic interventions, as they are more efficient when leukemia burden is low …

Flow cytometric monitoring of hematopoietic reconstitution in myeloablated patients following allogeneic transplantation

G Fritsch, V Witt, J Dubovsky, S Matthes, C Peters… - …, 1999 - Taylor & Francis
Background We report a routine flow cytometric (FACS) approach to quantify circulating
leukocytes (NC) in myeloablated patients before and during regeneration after allogeneic …

Delayed attainment of full donor chimaerism following alemtuzumab‐based reduced‐intensity conditioning haematopoeitic stem cell transplantation for acute myeloid …

ZY Lim, L Pearce, AY Ho, L Barber… - British journal of …, 2007 - Wiley Online Library
This prospective study evaluated the kinetics of lymphoid (CD3) engraftment in 110 patients
with acute myeloid leukaemia (AML) and myelodysplastic syndromes (MDS) after allogeneic …

Sequential high-sensitivity mutational and chimerism analyses predict responses to post-transplant salvage therapies in MDS

F Ebeling, J Illman, M Kankainen, M Kontro… - Bone Marrow …, 2023 - nature.com
The generally dismal outcome of MDS relapse after allogeneic stem cell transplantation
(SCT) may improve with early detection and salvage interventions, such as withdrawal of …

SNP-based next-generation sequencing reveals low-level mixed chimerism after allogeneic hematopoietic stem cell transplantation

J Kim, IS Hwang, S Shin, JR Choi, ST Lee - Annals of Hematology, 2018 - Springer
Dear Editor, Allogeneic hematopoietic stem cell transplantation (HSCT) is an important
treatment modality for various malignant and non-malignant hematological disorders …

Extramedullary manifestation of a donor-derived acute myeloid leukemia in a liver transplant patient

M Subklewe, M Nagy, C Schoch, S Jenisch, R Siebert… - Leukemia, 2004 - nature.com
Extramedullary manifestation of a donor-derived acute myeloid leukemia in a liver transplant
patient number of patients studied is limited and all transplant recipients received a dose …

Assessment of chimerism by next generation sequencing: A comparison to STR/qPCR methods

D Brow, H Shike, J Kendrick, L Pettersson, S Mineishi… - Human Immunology, 2024 - Elsevier
Chimerism analysis is used to evaluate patients after allogeneic hematopoietic stem cell
transplant (allo-HSCT) for engraftment and minimal measurable residual disease (MRD) …

Multiplex real‐time quantitative polymerase chain reaction assay for rapid and sensitive detection of hematopoietic chimerism

S Nadvornikova, M Leontovycova, K Pegova… - HLA, 2018 - Wiley Online Library
The increase of mixed chimerism (MC) after allogeneic hematopoietic stem cell
transplantation has been associated with a high risk of relapse. A variety of techniques that …