In mammals, melanin is synthesized in a specialized secretory cell known as the
melanocyte. This cell is characterized by the presence of tyrosinase, which is responsible for …

In mammals, melanin is synthesized in specialized secretory cells known as melanocytes.
This cell is characterized by the presence of tyrosinase, which is responsible for the aerobic …

In mammals, melanin is synthesized in specialized unicellular secretory glands, known as
melanocytes. Tyrosinase*[EC 1.10. 3.1, o-diphenol: 02 oxidoreductase] catalyzes the …

Localization of tyrosinase or catechol oxi dase [EC 1. 10. 3. 1, o-diphenol: 02 oxidoreduc
tase, mouse melanoma] activity in cell particles was first reported by H errmann and Boss (1) …

Human malignant melanocytes show characteristic morphologic modifications which are
particularly evident in their specific organelles: melanosomes. These modifications are …

For twenty years, tyrosinase activity has been known to be attached to cytoplasmic
particulates. In 1945, Herrmann and Boss [5] demonstrated the presence in the ciliary body …

Tyrosinase is constitutively expressed by normal melanocytes and melanoma cells. Both
melanocytes and melanoma cells are proposed to differentiate from an early melanocyte …

Melanin and protein synthesis in cultured mouse pigment cells (440W and 440B) were
studied by autoradiography and scintillation counting. The non-pigmented 440W cells did …

In mammals, melanin formation occurs only in melanosomes within the melanocyte, where
tyrosinases are most highly accumulated; however tyrosinases exist as precursors of …

The activity of tyrosinase, the rate-limiting enzyme for melanin synthesis, is higher in Black
skin melanocytes than in melanocytes derived from Caucasian skin. This variation in …