Sepsis and septic shock are common life-threatening pathologies associated with high
mortality and substantial costs for healthcare system. Clinical guidelines and bundles for the …

Sepsis has been around since the dawn of time, having been described for more than 2000
years, although clinical definitions are recent. The consensus sepsis definitions have …

Sepsis is one of the main causes of morbidity and mortality in critically ill patients despite the
use of modern antibiotics and resuscitation therapies. Outcomes in sepsis have improved …

Sepsis is a common condition with high morbidity and mortality. Although many patients may
require critical care, this article considers the features of sepsis that are of most relevance to …

Introduction Sepsis remains a common problem in critically ill patients. Discussion
Considerable advances have been made in our understanding of the pathophysiology of …

Importance Definitions of sepsis and septic shock were last revised in 2001. Considerable
advances have since been made into the pathobiology (changes in organ function …

There has been a significant evolution in the definition and management of sepsis over the
last three decades. This is driven in part due to the advances made in our understanding of …

Sepsis is a clinical syndrome encompassing physiologic and biological abnormalities
caused by a dysregulated host response to infection. Sepsis progression into septic shock is …

Sepsis is the systemic inflammatory response to infection [1]. Sepsis and its sequelae
represent progressive stages of the same illness in which a systemic response to an …

Sepsis is a major growing global burden and a major challenge to intensive care clinicians,
researchers, guideline committee members and policy makers, because of its high and …