The hypothalamic‐pituitary‐adrenal (HPA) axis is integrated in the human stress system and
controls the metabolism of many cell systems in the body. Therefore, hypofunction or …

306 extent on the etiology of the disorder. Hypercortisolism is a diagnosis that is frequently
suspected but seldom confirmed. The most common cause of hypercortisolism is the …

The most common ectopic production of a pituitary hormone is the one of ACTH leading to
Cushing's syndrome. Ectopic ACTH-hypersecretion is the cause of Cushing's syndrome in …

Adrenochromaffin cells have been shown to physiologically synthesize and secrete ACTH.
We have thus hypothesized that excessive intraadrenal ACTH production may be involved …

An adrenal tumour was incidentally discovered with no clinical signs of Cushing's syndrome.
The endocrine evaluation revealed the unique hormonal constellation of an increased …

A 47-yr-old woman with severe Cushing's syndrome had a bronchial carcinoid secreting
ACTH and corticotropin-releasing hormone (CRH) and associated pituitary corticotroph …

Publisher Summary This chapter focuses on adrenocorticotropin and related peptides in
nonendocrine tumors. The ectopic adrenocorticotropic hormone (ACTH) syndrome is usually …

To provide further evidence for the identification of the cell type responsible for the
production of adrenocorticotrophin (ACTH), the effects of acute and chronic administration of …

A wide variety of autocrine/paracrine bioactive signals are able to modulate corticosteroid
secretion in the human adrenal gland. These regulatory factors, released in the vicinity of …

Objective To examine whether inhibition of endogenous adrenocorticotropin (ACTH)
secretion in patients with Cushing syndrome affects the expression of the ACTH receptor …